Evidence map›Paper›PMID 37474107›Full record

ArticleEuropean journal of endocrinology2023

Etiology, morphology, and outcomes of adrenal calcifications in 540 adult patients-a retrospective single-center study.

Annop Kittithaworn, Prerna Dogra, Leili Rahimi, Rashi Sandooja, Irina Bancos

Open access · greenAbstract read
In one paragraph

Article in European journal of endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Guideline
  2. Article
  3. An incidental adrenal discovery.JCEM case reports · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Annop KittithawornDivision of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA.
Prerna DograDivision of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0002-1842-1968
Leili RahimiDivision of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA.
Rashi SandoojaDivision of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA.
Irina BancosDivision of Endocrinology, Mayo Clinic, Rochester, MN 55905, USA.ORCID 0000-0001-9332-2524
Mayo Clinic · US

Funding

Skeletal Consequences of Mild Autonomous Cortisol SecretionK23DK121888 · NIDDK · MAYO CLINIC ROCHESTER · PI BANCOS, IRINA · 2019 to 2022
$630k
Impact of menopause associated adrenal aging on cognitive function and Alzheimer dementia neuroimaging biomarkersR03AG071934 · NIA · MAYO CLINIC ROCHESTER · PI BANCOS, IRINA · 2022 to 2023
$324k
Impact of abnormal steroid metabolome on cellular senescence, frailty and cognitionR03DK132121 · NIDDK · MAYO CLINIC ROCHESTER · PI BANCOS, IRINA · 2022 to 2023
$239k
NIA NIH HHS R03 AG071934NIDDK NIH HHS K23 DK121888NIDDK NIH HHS R03 DK132121NIH HHS K23DK121888
6 · The paper itself

Abstract

Sparse data are available on the etiology, morphology, clinical presentation, and outcomes of adrenal calcification. In this single-center retrospective study of 540 consecutive patients (median age 65 years, 45% women) with adrenal calcification on computed tomography (December 2017 to January 2021), most were discovered incidentally (472, 87%). The commonest etiology was idiopathic (389, 72%), followed by the adrenal tumor (113, 21%), hemorrhage (29, 5%), and infiltrative disease (7, 1%). Calcified adrenal tumors were predominantly benign (92, 81%) and primarily adenomas (63, 69%), whereas the most common calcified adrenal malignancy (16, 18%) was metastasis (12, 67%). Calcification (unilateral 94%, bilateral 6%) morphology varied from punctate (313, 58%) to coarse (165, 30%), linear/curvilinear (46, 9%), and rim-like (16, 3%). In summary, adrenal calcifications are usually incidentally discovered unilateral, punctate, or coarse lesions of unclear etiology. Most calcified adrenal tumors are benign and <20% malignant or pheochromocytomas.

Indexed as

AdenomaAdrenal Gland NeoplasmsCalcinosisPheochromocytomaAdultAgedFemaleHumansMaleRetrospective StudiesTomography, X-Ray Computedadrenal massadrenal tumorcalcifiedcomputed tomographyprimary adrenal insufficiency

Identifiers

PMID37474107
PMCPMC10387451
OpenAlexW4384923958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.