Evidence map›Paper›PMID 37473780›Full record

Trial reportEndoscopy2024

Endoscopic ultrasound-guided choledochoduodenostomy using single-step lumen-apposing metal stents for primary drainage of malignant distal biliary obstruction (SCORPION-p): a prospective pilot study.

Jeska A Fritzsche, Paul Fockens, Marc G Besselink, Olivier R Busch, Freek Daams, Nahid S M Montazeri, Johanna W Wilmink, Rogier P Voermans, Roy L J Van Wanrooij

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jeska A FritzscheDepartment of Gastroenterology and Hepatology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Paul FockensDepartment of Gastroenterology and Hepatology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Marc G BesselinkAmsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.
Olivier R BuschAmsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.
Freek DaamsAmsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.
Nahid S M MontazeriAmsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.
Johanna W WilminkAmsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.
Rogier P Voermans *Department of Gastroenterology and Hepatology, Amsterdam UMC, location University of Amsterdam, Amsterdam, The Netherlands.
Roy L J Van Wanrooij *Amsterdam Gastroenterology Endocrinology Metabolism, Research Institute, Amsterdam, The Netherlands.ORCID 0000-0003-0477-4532
Amsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to assess the safety and feasibility of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) using a lumen-apposing metal stent (LAMS) as a primary drainage strategy in patients with distal malignant biliary obstruction (MBO).

methodsA prospective, single-center, pilot study was conducted in patients with pathology-confirmed MBO without gastric outlet obstruction. The primary outcome was technical success. Secondary outcomes included clinical success, adverse events (AEs), and reinterventions. The study was registered in the Netherlands Trial Registry (registry number NL9757).

results22 patients were enrolled (median age 69.5 years [interquartile range 64-75.3]). Technical success was achieved in 20/22 patients (91 %). AEs occurred in one patient, namely perforation following inadequate stent deployment (5 %), which was treated in the same procedure. Clinical success was achieved in 19/22 patients (86 %). Stent dysfunction was observed in 11/20 patients (55 %) after technically successful EUS-CDS: two patients were treated conservatively and nine patients underwent reintervention(s). One patient died within ≤ 30 days due to fulminant disease progression.

conclusionsThe results confirmed the safety and feasibility of EUS-CDS using LAMS as a primary drainage strategy. The high incidence of stent dysfunction should be improved before EUS-CDS with LAMS can be seen as a valid alternative to endoscopic retrograde cholangiopancreatography.

Indexed as

CholedochostomyCholestasisDrainageAgedEndosonographyHumansPilot ProjectsProspective StudiesStentsUltrasonography, Interventional

Identifiers

PMID37473780
PMCPMC11321721
OpenAlexW4384924726

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.