Evidence map›Paper›PMID 37471581›Full record

ArticleVeterinary medicine and science2023

The detection and full genomic characterization of domestic cat Orthohepadnaviruses from Türkiye.

Ece Adıgüzel, Eda Erdem-Şahinkesen, Bahattin Taylan Koç, Cansu Demirden, Tuba Çiğdem Oğuzoğlu

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Article in Veterinary medicine and science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

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10citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  5. Conserved Functions ofInternational journal of molecular sciences · 2024
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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Ece AdıgüzelRepublic of Türkiye Ministry of Agriculture and Forestry, Atkaracalar District Directorate, Cankiri, Türkiye.ORCID 0000-0003-3316-299X
Eda Erdem-ŞahinkesenGraduate School of Health Sciences, Ankara University, Ankara, Türkiye.ORCID 0000-0002-8116-0721
Bahattin Taylan KoçDepartment of Virology, Faculty of Veterinary Medicine, Adnan Menderes University, Aydin, Türkiye.ORCID 0000-0002-4279-6233
Cansu DemirdenGraduate School of Health Sciences, Ankara University, Ankara, Türkiye.ORCID 0000-0003-2063-4302
Tuba Çiğdem OğuzoğluDepartment of Virology, Faculty of Veterinary Medicine, Ankara University, Ankara, Türkiye.ORCID 0000-0003-4021-2414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDomestic cat hepadnaviruses (DCHs) have been described as a novel virus that can infect cats.

objectiveThe aim of our study is the first identification and molecular characterizations of DCH infection in Turkish domestic cats.

methodsThe blood, organ and ascites fluid samples from 550 cats were randomly sampled. The presence of DCH nucleic acid was investigated by using both in the literature and newly designed primers.

resultsIt was found that the hepadnavirus positivity rate is 4% (22/550) in Türkiye. The full genomic characterization was performed on 13 of 22 samples, and others were characterized as nearly full genome. In this study, we highlight that whole blood samples should be also screened for DCH, not only serum samples as has frequently been done in other studies. DCH-infected cats were also found positive (54.54%, 12/22) for Feline leukaemia virus infection. BLAST results revealed that Turkish DCHs have 86.32%-99.08% homology with strains in the GenBank database, enabling us to construct phylogenetic trees.

conclusionsAccording to this study's results, it is suggested that this infection should be added to veterinary diagnostic panels worldwide. Additionally, we suggest that our new synthesized primers for the amplification of X gene can also be used for diagnosis.

Indexed as

HepadnaviridaeOrthohepadnavirusAnimalsCatsGenome, ViralGenomicsPhylogenydomestic cat hepadnavirusmolecular detectionTürkiye

Identifiers

PMID37471581
PMCPMC10508501

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.