Evidence map›Paper›PMID 37471486›Full record

ArticleCirculation research2023

Cardiac Fibrosis Mitigated by an Endogenous Negative Regulator of HDAC.

Michael P Lazaropoulos, John W Elrod

Abstract readEditorialComment
In one paragraph

Article in Circulation research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael P LazaropoulosCardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.
John W ElrodCardiovascular Research Center, Lewis Katz School of Medicine at Temple University, Philadelphia, PA.ORCID 0000-0003-3925-2224

Funding

Small and large animal surgery, physiology and histologyP01HL134608 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Raj Kishore · 2017 to 2026
$21.0M
Targeting Pathways Involved in Cardiac Injury for Novel Repair StrategiesP01HL147841 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI KOCH, WALTER J. · 2020 to 2024
$11.4M
Molecular composition of the mitochondrial calcium uniporter and cardiac pathophysiologyR01HL142271 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI ELROD, JOHN WILLIAM, HAJNOCZKY, GYORGY · 2018 to 2021
$3.0M
Mechanisms of mitochondrial calcium exchange in heart failureR01HL123966 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2014 to 2018
$2.3M
Mitochondria and metabolism in neurodegenerationRF1NS121379 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2021 to 2021
$2.3M
Novel Molecular Mechanisms of Programmed NecrosisR01HL136954 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2017 to 2020
$1.6M
Mitochondria and metabolism in neurodegenerationR01NS121379 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2024 to 2025
$1.5M
The Role of Acetyl-CoA Metabolism in Epigenetic Regulation of Myofibroblast DifferentiationF30HL152564 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI LAZAROPOULOS, MICHAEL · 2020 to 2024
$204k
NHLBI NIH HHS F30 HL152564NHLBI NIH HHS P01 HL134608NHLBI NIH HHS P01 HL147841NHLBI NIH HHS R01 HL123966NHLBI NIH HHS R01 HL136954NHLBI NIH HHS R01 HL142271NINDS NIH HHS R01 NS121379NINDS NIH HHS RF1 NS121379
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiomyopathiesFibroblastsFibrosisHumansMyocardiumMyofibroblastsagingEditorialsfibrosisheart failuremyofibroblastubiquitin

Identifiers

PMID37471486
PMCPMC10521147

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.