Evidence map›Paper›PMID 37471399›Full record

ArticlePloS one2023

Study protocol: How does cognitive flexibility relate to other executive functions and learning in healthy young adults?

Ke Tong, Yuan Ni Chan, Xiaoqin Cheng, Bobby Cheon, Michelle Ellefson, Restria Fauziana, Shengchuang Feng, Nastassja Fischer, Balázs Gulyás, Natalie Hoo and 25 more

Registry-linked trialAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07556250 (Investigating Cognitive Flexibility Training), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07556250 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Investigating Cognitive Flexibility Training

TypeinterventionalSponsorNanyang Technological UniversityRan2026 to 2026Enrolled225ConditionsHealthyArmsExperimental (Implicit Training): Structure Learning Training, Active Control (Explicit Training): 'All You Can E.T.'
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Ke TongNanyang Technological University, Singapore, Singapore.ORCID 0000-0001-6226-1044
Yuan Ni ChanNanyang Technological University, Singapore, Singapore.
Xiaoqin ChengNanyang Technological University, Singapore, Singapore.ORCID 0000-0002-4560-1403
Bobby CheonNational Institutes of Health, Bethesda, Maryland, United States of America.ORCID 0000-0001-6815-619X
Michelle EllefsonUniversity of Cambridge, Cambridge, United Kingdom.
Restria FauzianaNanyang Technological University, Singapore, Singapore.
Shengchuang FengNanyang Technological University, Singapore, Singapore.
Nastassja FischerNanyang Technological University, Singapore, Singapore.ORCID 0000-0002-1383-1917
Balázs GulyásNanyang Technological University, Singapore, Singapore.
Natalie HooNanyang Technological University, Singapore, Singapore.
David HungNational Institute of Education, Singapore, Singapore.
Kastoori KalaivananNanyang Technological University, Singapore, Singapore.
Christelle LangleyUniversity of Cambridge, Cambridge, United Kingdom.
Kean Mun LeeNanyang Technological University, Singapore, Singapore.ORCID 0000-0001-7582-3253
Li Ling LeeNanyang Technological University, Singapore, Singapore.
Timothy LeeNational Institute of Education, Singapore, Singapore.ORCID 0000-0003-0455-3828
Irene MelaniNanyang Technological University, Singapore, Singapore.
Nadhilla MeliaNanyang Technological University, Singapore, Singapore.
Jia Ying PeiNanyang Technological University, Singapore, Singapore.
Lisha RaghaniNanyang Technological University, Singapore, Singapore.
Yoke Loo SamNanyang Technological University, Singapore, Singapore.ORCID 0000-0001-8770-2651
Peter SeowNational Institute of Education, Singapore, Singapore.
John SucklingUniversity of Cambridge, Cambridge, United Kingdom.
Yan Fen TanNanyang Technological University, Singapore, Singapore.
Chew Lee TeoNational Institute of Education, Singapore, Singapore.
Ryutaro UchiyamaNanyang Technological University, Singapore, Singapore.ORCID 0000-0003-2444-9980
Hui Shan YapNanyang Technological University, Singapore, Singapore.
Georgios ChristopoulosNanyang Technological University, Singapore, Singapore.
Henriette HendriksUniversity of Cambridge, Cambridge, United Kingdom.ORCID 0000-0001-9420-6816
Annabel ChenNanyang Technological University, Singapore, Singapore.ORCID 0000-0002-1540-5516
Trevor RobbinsUniversity of Cambridge, Cambridge, United Kingdom.
Barbara SahakianUniversity of Cambridge, Cambridge, United Kingdom.
Zoe KourtziUniversity of Cambridge, Cambridge, United Kingdom.
Victoria LeongNanyang Technological University, Singapore, Singapore.
CLIC Phase 1 Consortium

Funding

Psychosocial influences on appetite and eating behaviorZIAHD009004 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI CHEON, BOBBY · 2022 to 2025
$8.1M
Biotechnology and Biological Sciences Research Council BB/P021255/1Wellcome Trust 205067/Z/16/Z
6 · The paper itself

Abstract

backgroundCognitive flexibility (CF) enables individuals to readily shift from one concept or mode of practice/thoughts to another in response to changes in the environment and feedback, making CF vital to optimise success in obtaining goals. However, how CF relates to other executive functions (e.g., working memory, response inhibition), mental abilities (e.g., creativity, literacy, numeracy, intelligence, structure learning), and social factors (e.g., multilingualism, tolerance of uncertainty, perceived social support, social decision-making) is less well understood. The current study aims to (1) establish the construct validity of CF in relation to other executive function skills and intelligence, and (2) elucidate specific relationships between CF, structure learning, creativity, career decision making and planning, and other life skills.

methodsThis study will recruit up to 400 healthy Singaporean young adults (age 18-30) to complete a wide range of cognitive tasks and social questionnaires/tasks. The richness of the task/questionnaire battery and within-participant administration enables us to use computational modelling and structural equation modelling to examine connections between the latent constructs of interest. SIGNIFICANCE AND IMPACT: The current study is the first systematic investigation into the construct validity of CF and its interrelationship with other important cognitive skills such as learning and creativity, within an Asian context. The study will further explore the concept of CF as a non-unitary construct, a novel theoretical proposition in the field. The inclusion of a structure learning paradigm is intended to inform future development of a novel intervention paradigm to enhance CF. Finally, the results of the study will be useful for informing classroom pedagogy and the design of lifelong learning policies and curricula, as part of the wider remit of the Cambridge-NTU Centre for Lifelong Learning and Individualised Cognition (CLIC).

Indexed as

CognitionExecutive FunctionAdolescentAdultCreativityHumansLearningMemory, Short-TermYoung Adult

Identifiers

PMID37471399
PMCPMC10358919

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.