Evidence map›Paper›PMID 37471284›Full record

ReviewPLoS genetics2023

Building the synaptonemal complex: Molecular interactions between the axis and the central region.

Spencer G Gordon, Ofer Rog

Abstract readReview
In one paragraph

Review in PLoS genetics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. The synaptonemal complex aligns meiotic chromosomes by wetting.bioRxiv : the preprint server for biology · 2024
    Article
  10. Review
  11. A suppressor screenProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  12. A suppressor screenbioRxiv : the preprint server for biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Spencer G GordonSchool of Biological Sciences and Center for Cell and Genome Sciences, University of Utah, Salt Lake City, Utah, United States of America.ORCID 0000-0001-9787-406X
Ofer RogSchool of Biological Sciences and Center for Cell and Genome Sciences, University of Utah, Salt Lake City, Utah, United States of America.ORCID 0000-0001-6558-6194

Funding

Structure and dynamics of meiotic chromosomesR35GM128804 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Ofer Rog · 2018 to 2026
$4.1M
NIGMS NIH HHS R35 GM128804
6 · The paper itself

Abstract

The successful delivery of genetic material to gametes requires tightly regulated interactions between the parental chromosomes. Central to this regulation is a conserved chromosomal interface called the synaptonemal complex (SC), which brings the parental chromosomes in close proximity along their length. While many of its components are known, the interfaces that mediate the assembly of the SC remain a mystery. Here, we survey findings from different model systems while focusing on insight gained in the nematode C. elegans. We synthesize our current understanding of the structure, dynamics, and biophysical properties of the SC and propose mechanisms for SC assembly.

Indexed as

Caenorhabditis elegans ProteinsSynaptonemal ComplexAnimalsCaenorhabditis elegansChromosome PairingMeiosisCaenorhabditis elegans Proteins

Identifiers

PMID37471284
PMCPMC10359014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.