Evidence map›Paper›PMID 37471216›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2023

Exercise-induced changes to the fiber type-specific redox state in human skeletal muscle are associated with aerobic capacity.

James Shadiow, Edwin R Miranda, Ryan K Perkins, Corey E Mazo, Zhen Lin, Kendell N Lewis, Jacob T Mey, Thomas P J Solomon, Jacob M Haus

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

James ShadiowSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-0293-6753
Edwin R MirandaSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0003-2370-4118
Ryan K PerkinsSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.
Corey E MazoSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.
Zhen LinSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.
Kendell N LewisSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.
Jacob T MeyPennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, United States.ORCID 0000-0001-6826-7762
Thomas P J SolomonBlazon Scientific, London, United Kingdom.ORCID 0000-0002-0579-284X
Jacob M HausSchool of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States.ORCID 0000-0002-8048-2470
University of Michigan · USPennington Biomedical Research Center · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Mehboob A Hussain · 2013 to 2026
$24.3M
Strategies and Functional Outcomes of Enhancing in Vivo Production of Soluble Rage IsoformsR01DK109948 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAUS, JACOB M · 2016 to 2020
$3.1M
Exploring regulatory mechanisms of glyoxalase-1R21AG081916 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAUS, JACOB M · 2023 to 2024
$429k
NIA NIH HHS R21 AG081916NIDDK NIH HHS P30 DK020572NIDDK NIH HHS R01 DK109948
6 · The paper itself

Abstract

The benefits of exercise involve skeletal muscle redox state alterations of nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). We determined the fiber-specific effects of acute exercise on the skeletal muscle redox state in healthy adults. Muscle biopsies were obtained from 19 participants (11 M, 8 F; 26 ± 4 yr) at baseline (fasted) and 30 min and 3 h after treadmill exercise at 80% maximal oxygen consumption (V̇o

Indexed as

Muscle, SkeletalNADAdultExerciseHumansMuscle Fibers, SkeletalMyosin Heavy ChainsOxidation-ReductionMyosin Heavy ChainsNADautofluorescenceexercise physiologyflavoproteinsNAD/NADHoxygen delivery

Identifiers

PMID37471216
PMCPMC10538995
OpenAlexW4384926524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.