Evidence map›Paper›PMID 37470944›Full record

ReviewCurrent hypertension reports2023

Lifestyle Medicine as a Treatment for Resistant Hypertension.

Fernando Ribeiro, Manuel Teixeira, Alberto J Alves, Andrew Sherwood, James A Blumenthal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Fernando RibeiroInstitute of Biomedicine (iBiMED), School of Health Sciences, University of Aveiro, Aveiro, Portugal.ORCID 0000-0001-9094-1493
Manuel TeixeiraInstitute of Biomedicine (iBiMED), School of Health Sciences, University of Aveiro, Aveiro, Portugal.ORCID 0000-0001-6364-0011
Alberto J AlvesUniversity of Maia, Research Center in Sports Sciences, Health Sciences and Human Development, Castêlo da Maia, Portugal.ORCID 0000-0001-9484-7349
Andrew SherwoodDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, 27710, USA.ORCID 0000-0001-9067-185X
James A BlumenthalDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, 27710, USA. james.blumenthal@duke.edu.ORCID 0000-0003-3789-0935
University of Aveiro · PTDuke Medical Center · USDuke University · USInstituto Superior da Maia · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewApproximately 10% of the adults with hypertension fail to achieve the recommended blood pressure treatment targets on 3 antihypertensive medications or require ≥ 4 medications to achieve goal. These patients with 'resistant hypertension' have an increased risk of target organ damage, adverse clinical events, and all-cause mortality. Although lifestyle modification is widely recommended as a first-line approach for the management of high blood pressure, the effects of lifestyle modifications in patients with resistant hypertension has not been widely studied. This review aims to provide an overview of the emerging evidence on the benefits of lifestyle modifications in patients with resistant hypertension, reviews potential mechanisms by which lifestyles may reduce blood pressure, and discusses the clinical implications of the recent findings in this field. RECENT

findingsEvidence from single-component randomized clinical trials demonstrated that aerobic exercise, weight loss and dietary modification can reduce clinic and ambulatory blood pressure in patients with resistant hypertension. Moreover, evidence from multi-component trials involving exercise and dietary modification and weight management can facilitate lifestyle change, reduce clinic and ambulatory blood pressure, and improve biomarkers of cardiovascular risk. This new evidence supports the efficacy of lifestyle modifications added to optimized medical therapy in reducing blood pressure and improving cardiovascular risk biomarkers in patients with resistant hypertension. These findings need to be confirmed in larger studies, and the persistence of benefit over extended follow-up needs further study.

Indexed as

HypertensionAdultAntihypertensive AgentsBlood PressureBlood Pressure Monitoring, AmbulatoryExerciseHumansLife StyleAntihypertensive AgentsExerciseHypertensionLifestyleNutritionPhysical activity

Identifiers

PMID37470944
OpenAlexW4384819792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.