Evidence map›Paper›PMID 37470705›Full record

ArticleeLife2023

Protein compactness and interaction valency define the architecture of a biomolecular condensate across scales.

Anton A Polyansky, Laura D Gallego, Roman G Efremov, Alwin Köhler, Bojan Zagrovic

Abstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Adaptive Disorder as the Hallmark of Nanobodies Antigen-Binding Loops.Journal of chemical information and modeling · 2026
    Article
  3. Article
  4. Article
  5. A molecular grammar for programmable multiphase protein-RNA vesicles.bioRxiv : the preprint server for biology · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Exploring RNA destabilization mechanisms in biomolecular condensates through atomistic simulations.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  15. Article
  16. Review
  17. Article
  18. An Atomistic View on the Mechanism of Diatom Peptide-Guided Biomimetic Silica Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anton A Polyansky *Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.ORCID https://orcid.org/0000-0002-1011-2706
Laura D Gallego *Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.
Roman G EfremovMM Shemyakin and Yu A Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russian Federation.
Alwin KöhlerMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.
Bojan ZagrovicMax Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria.

Funding

Austrian Science Fund FWF F79Austrian Science Fund FWF P 30550Austrian Science Fund FWF P 30680-B21
6 · The paper itself

Abstract

Non-membrane-bound biomolecular condensates have been proposed to represent an important mode of subcellular organization in diverse biological settings. However, the fundamental principles governing the spatial organization and dynamics of condensates at the atomistic level remain unclear. The

Indexed as

Biomolecular CondensatesFungal ProteinsEntropyFractalsMolecular Dynamics SimulationFungal Proteinsbiomolecular condensatecolloiddisordered proteinfractal clusterLarge1liquid-liquid phase separationmolecular biophysicsphysics of living systemsS. cerevisiaestructural biology

Identifiers

PMID37470705
PMCPMC10406433

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.