Evidence map›Paper›PMID 37470296›Full record

ArticleThe Laryngoscope2024

The Rate of Occult Lesion Diagnosis in a Large Bell's Palsy Cohort.

Sandhya Kalavacherla, Eric Du, Víctor de Cos, Leo Meller, Benjamin Ostrander, Morgan Davis, Jacqueline Greene

Open access · hybridAbstract read
In one paragraph

Article in The Laryngoscope, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sandhya KalavacherlaSchool of Medicine, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-0485-9042
Eric DuSchool of Medicine, University of California San Diego, La Jolla, California, USA.
Víctor de CosSchool of Medicine, University of California San Diego, La Jolla, California, USA.
Leo MellerSchool of Medicine, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-9013-8227
Benjamin OstranderDepartment of Otolaryngology-Head & Neck Surgery, University of California San Diego, San Diego, California, USA.ORCID 0000-0002-8187-8557
Morgan DavisDepartment of Otolaryngology-Head & Neck Surgery, University of California San Diego, San Diego, California, USA.
Jacqueline GreeneDepartment of Otolaryngology-Head & Neck Surgery, University of California San Diego, San Diego, California, USA.
University of California San Diego · US

Funding

UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Otolaryngology Training in Immunology, Virology and Molecular BiologyR25DC020173 · NIDCD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joseph A Califano · 2022 to 2026
$1.4M
NIDCD NIH HHS R25 DC020173NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

objectivesWe characterize occult lesion diagnosis rates after initial Bell's palsy diagnoses.

methodsA de-identified database of all facial palsy patients who presented to an extensive health care system across 22 years was created using Epic SlicerDicer. Among patients with Bell's palsy diagnoses, we extracted demographic and any subsequent occult lesion diagnosis data across various clinical sites. Descriptive and multivariable regression analyses comparing patients with occult lesion diagnoses made at different time points were included.

resultsAmong the total 3912 facial palsy patients, 2240 had Bell's palsy diagnoses, of which 217 (9.7%) had subsequent lesion diagnoses at a median (IQR) of 12.3 (4.2, 23.8) months, consisting of cranial nerve neoplasms (62.2%), parotid gland neoplasms (34.1%), and cholesteatomas (3.7%). Although a large proportion of total lesions were diagnosed within the first 3 months (19.8%), 69.5% were diagnosed after 6 months. There were no demographic differences among patients diagnosed with different lesion types, but Asian patients were more likely to be diagnosed with occult lesions after 12 months after Bell's palsy diagnosis compared with white patients (odds ratio = 6.2, p = 0.001).

conclusionsIn one of the largest Bell's palsy cohorts to date, we identified a 9.7% occult lesion diagnosis rate at a median of 12.3 months after Bell's palsy diagnosis. These data underscore the importance of timely workup for occult lesions in cases of facial palsy with no signs of recovery after 3-4 months. LEVEL OF EVIDENCE: 4 Laryngoscope, 134:911-918, 2024.

Indexed as

Bell PalsyFacial ParalysisHumansBell's palsycholesteatomacranial nerve schwannomafacial palsyoccult lesionsparotid gland neoplasm

Identifiers

PMID37470296
PMCPMC11023743
OpenAlexW4384819216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.