Evidence map›Paper›PMID 37469844›Full record

ArticleEncephalitis (Seoul, Korea)2021

Proportion of peripheral regulatory T cells in patients with autoimmune encephalitis.

Jung-Ick Byun, Ji-Yeon Bae, Jangsup Moon, Soon-Tae Lee, Keun-Hwa Jung, Kyung-Il Park, Manho Kim, Sang Kun Lee, Kon Chu

Open access · diamondAbstract read
In one paragraph

Article in Encephalitis (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Regulatory T cell profiles in patients withEncephalitis (Seoul, Korea) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jung-Ick ByunDepartment of Neurology, Kyung Hee University Hospital at Gangdong, Kyung Hee University College of Medicine, Seoul, Korea.
Ji-Yeon BaeDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Jangsup MoonDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Soon-Tae LeeDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Keun-Hwa JungDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Kyung-Il ParkDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Manho KimDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Sang Kun LeeDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.
Kon ChuDepartment of Neurology, Seoul National University Hospital, Seoul, Korea.ORCID 0000-0001-5863-0302
Seoul National University · KRKyung Hee University Hospital at Gangdong · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Regulatory T cells (Tregs) play a crucial role in maintaining immune tolerance. Any deficiency or dysfunction of the Tregs can influence the pathogenesis of autoimmune disease. This study aimed to assess the role of Tregs among patients with autoimmune encephalitis (AE) with different autoantibody types and to evaluate their association with clinical features. Methods: This was a cross-sectional observational study involving 29 patients with AE. Peripheral blood was sampled from each patient for flow cytometric analysis. Proportions of CD4 Results: Five patients had synaptic autoantibodies, five had paraneoplastic autoantibodies, and the others were of an undetermined type. The proportion of CD4 Conclusion: The results of the present study suggest that Tregs may play different roles according to the type of AE and may be linked to disease severity.

Indexed as

AntibodiesAutoimmune encephalitisIntravenous immunoglobulinsRegulatory T-lymphocytes

Identifiers

PMID37469844
PMCPMC10295879
OpenAlexW3153549531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.