ArticleFrontiers in neuroscience2023
Relationship between temporal dynamics of intrinsic brain activity and motor function remodeling in patients with acute BGIS.
Article in Frontiers in neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 4 citations in OpenAlex.
- Mirror therapy reduces excessive variability of motor network in stroke patients: a randomized controlled trial.European journal of physical and rehabilitation medicine · 2025Trial
- Altered temporal variability-based functional reorganization of brain networks predicts motor outcome after stroke.Journal of neuroengineering and rehabilitation · 2026Article
- Static and temporal dynamic changes in brain activity in patients with post-stroke balance dysfunction: a pilot resting state fMRI.Frontiers in neuroscience · 2025Article
- Alterations of dynamic and static brain functional activities and integration in stroke patients.Frontiers in neuroscience · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: patients with acute basal ganglia ischemic stroke (BGIS) show changes in local brain activity represented by the amplitude of low-frequency fluctuation (ALFF), but the time-varying characteristics of this local nerve activity are still unclear. This study aimed to investigate the abnormal time-varying local brain activity of patients with acute BGIS by using the ALFF method combined with the sliding-window approach. Methods: In this study, 34 patients with acute BGIS with motor dysfunction and 44 healthy controls (HCs) were recruited. The dynamic amplitude of low-frequency fluctuation (dALFF) was employed to detect the alterations in brain activity induced by acute BGIS patients. A two-sample Results: Compared with HCs, the activity of neurons in the left temporal pole (TP), parahippocampal gyrus (paraHIP), middle occipital gyrus (MOG), dorsolateral superior frontal gyrus (SFGdl), medial cingulate cortex (MCC), right rectus, precuneus (PCu) and right cerebellum crus1 were significantly increased in patients with BGIS. In addition, we found that there was a negative correlation ( Conclusion: The pattern of intrinsic brain activity variability was altered in patients with acute BGIS compared with HCs. The abnormal dALFF variability might be a potential tool to assess motor function in patients with acute BGIS and potentially inform the diagnosis of this disease.
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