Evidence map›Paper›PMID 37469720›Full record

ArticleWorld journal of clinical cases2023

Age, blood tests and comorbidities and AIMS65 risk scores outperform Glasgow-Blatchford and pre-endoscopic Rockall score in patients with upper gastrointestinal bleeding.

Bianca Codrina Morarasu, Victorita Sorodoc, Anca Haisan, Stefan Morarasu, Cristina Bologa, Raluca Ecaterina Haliga, Catalina Lionte, Emilia Adriana Marciuc, Mohammed Elsiddig, Diana Cimpoesu and 2 more

Open access · diamondAbstract read
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Article in World journal of clinical cases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Bianca Codrina MorarasuDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Victorita SorodocDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania. victorita.sorodoc@umfiasi.ro.
Anca HaisanDepartment of Emergency Medicine, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Stefan MorarasuSecond Department of Surgical Oncology, Regional Institute of Oncology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Cristina BologaDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Raluca Ecaterina HaligaDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Catalina LionteDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Emilia Adriana MarciucDepartment of Radiology, Emergency Hospital "Prof. Dr. N. Oblu", Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700309, Romania.
Mohammed ElsiddigDepartment of Gatroenterology, Beaumont Hospital, Dublin D09V2N0, Ireland.
Diana CimpoesuDepartment of Emergency Medicine, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Gabriel Mihail DimofteSecond Department of Surgical Oncology, Regional Institute of Oncology, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Laurentiu SorodocDepartment of Internal Medicine and Toxicology, Saint Spiridon University Regional Emergency Hospital, Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, Iasi 700111, Romania.
Grigore T. Popa University of Medicine and Pharmacy · ROBeaumont Hospital · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUpper gastrointestinal (GI) bleeding is a life-threatening condition with high mortality rates.

aimTo compare the performance of pre-endoscopic risk scores in predicting the following primary outcomes: In-hospital mortality, intervention (endoscopic or surgical) and length of admission (≥ 7 d).

methodsWe performed a retrospective analysis of 363 patients presenting with upper GI bleeding from December 2020 to January 2021. We calculated and compared the area under the receiver operating characteristics curves (AUROCs) of Glasgow-Blatchford score (GBS), pre-endoscopic Rockall score (PERS), albumin, international normalized ratio, altered mental status, systolic blood pressure, age older than 65 (AIMS65) and age, blood tests and comorbidities (ABC), including their optimal cut-off in variceal and non-variceal upper GI bleeding cohorts. We subsequently analyzed through a logistic binary regression model, if addition of lactate increased the score performance.

resultsAll scores had discriminative ability in predicting in-hospital mortality irrespective of study group. AIMS65 score had the best performance in the variceal bleeding group (AUROC = 0.772;

conclusionABC score is the most accurate in predicting in-hospital mortality in both mixed and non-variceal bleeding population. PERS and GBS should be used to determine need for endoscopic and surgical intervention, respectively. Lactate can be used as an additional tool to risk scores for predicting in-hospital mortality.

Indexed as

Age, blood tests and comorbiditiesAge older than 65Gastrointestinal bleedingGlasgow-BlatchfordPre-endoscopic RockallRisk score

Identifiers

PMID37469720
PMCPMC10353516
OpenAlexW4382877697

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.