Evidence map›Paper›PMID 37469533›Full record

ArticleAmerican journal of cardiovascular disease2023

The safety of deferred coronary angiography in COVID-19 patients with acute coronary syndrome: the Barts COVID recovered pathway.

Zhi Teoh, Krishnaraj S Rathod, Katrina Comer, Angelos Tyrlis, Fizzah A Choudry, Mick Ozkor, R Andrew Archbold, Oliver Guttmann, Andrew Wragg, Andreas Baumbach and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of cardiovascular disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Zhi TeohBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Krishnaraj S RathodBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Katrina ComerBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Angelos TyrlisBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Fizzah A ChoudryBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Mick OzkorBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
R Andrew ArchboldBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Oliver GuttmannBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Andrew WraggBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Andreas BaumbachBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Ajay K JainBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Anthony MathurBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
Daniel A JonesBarts Intervention Group, Interventional Cardiology, Barts Heart Centre, St. Bartholomew's Hospital West Smithfield, London, EC1A 7BE, UK.
St Bartholomew's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the safety and effectiveness of a novel pathway of deferrred invasive angiography in low-risk NSTEMI patients with concurrent COVID-19 infections; contrary to current UK guidelines recommending invasive coronary angiography in NSTEMI patients within 72 hours.

methodsThis was a single-centre, observational study of all NSTEMI patients referred for inpatient coronary angiography at Barts Heart Centre, between March 2020 and June 2022. Demographic, procedural and outcome data were collected as part of a national cardiac audit.

results201 COVID positive NSTEMI patients were referred for angiography at Barts Heart Centre. 10 patients died from COVID related respiratory complications prior to angiography. Therefore, 191 patients underwent deferred angiography (median time 16 days from COVID diagnosis). The median GRACE score was 128 (IQR 86-153). Troponin levels were significantly elevated on initial COVID diagnosis compared to time of their procedure. 73% patients had a culprit lesion identified. 61.2% receiving PCI. Patients were followed-up for a median of 363 days (IQR 120-485 days) with MACE rates of 7.3%. This is comparable to the MACE event for NSTEMI patients (n=4529) without COVID at our institution treated during the same time-period (8.1%).

conclusionThis study demonstrates the safety and effectiveness of deferred coronary angiography on a COVID-Recovered pathway after a period of medical management for patients presenting with NSTEMI and concurrent COVID-19 infection. There was no adverse signal associated with the wait for angiography with similar MACE rates to the non-deferred NSTEMI cohort without COVID-19.

Indexed as

Coronavirus-19deferred angiographynon-ST elevation MI

Identifiers

PMID37469533
PMCPMC10352812
OpenAlexW4384819951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.