Evidence map›Paper›PMID 37469375›Full record

ArticleAcute medicine & surgery

Severe acute respiratory distress syndrome caused by Otsujito.

Nobuhisa Hirasawa, Hajime Nakae, Kasumi Satoh, Kenji Yoshida, Manabu Okuyama

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nobuhisa HirasawaDepartment of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.ORCID https://orcid.org/0000-0001-9329-0534
Hajime NakaeDepartment of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.ORCID https://orcid.org/0000-0003-3733-3530
Kasumi SatohDepartment of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.
Kenji YoshidaDepartment of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.
Manabu OkuyamaDepartment of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan.
Akita University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Kampo prescriptions can cause drug-induced lung injury (DLI) and acute respiratory distress syndrome (ARDS). However, severe respiratory failure induced by Otsujito (OJT) is extremely rare. High-dose steroid pulse therapy is generally given to patients with severe DLI. Case Presentation: A 63-year-old man with respiratory distress was admitted to our hospital. The patient was diagnosed with severe ARDS caused by OJT, which had been prescribed 4 weeks prior to admission. Thus, OJT was discontinued, and intensive care for ARDS, including ventilation and prone positioning, was implemented. His respiratory condition rapidly improved after treatment with an initial methylprednisolone dose (1.5 mg/kg/day). He was extubated on day 4 and discharged on day 16. The steroid dose was gradually reduced and discontinued by day 116. Conclusion: A severe case of ARDS caused by OJT was successfully treated with low-dose steroids and specialized intensive care.

Indexed as

abnormalitydrug‐inducedKampoOtsujitosteroid

Identifiers

PMID37469375
PMCPMC10352571
OpenAlexW4384788610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.