Evidence map›Paper›PMID 37468978›Full record

ArticleBioPsychoSocial medicine2023

Physical exercise augmented cognitive behaviour therapy for older adults with generalised anxiety disorder (PEXACOG): a feasibility study for a randomized controlled trial.

Kristine Sirevåg, S H Stavestrand, T Sjøbø, T B Endal, H M Nordahl, E Andersson, I H Nordhus, Å Rekdal, K Specht, Å Hammar and 5 more

Erratum issued Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioPsychoSocial medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02690441 (Physical Exercise Augmented Cognitive Behaviour Therapy for Older Adults With Generalised Anxiety Disorder), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02690441 naactive not recruitingnot on this map

Physical Exercise Augmented Cognitive Behaviour Therapy for Older Adults With Generalised Anxiety Disorder

TypeinterventionalSponsorSolli Distriktspsykiatriske SenterRan2016 to 2026Enrolled53ConditionsGeneralized Anxiety DisorderArmsCognitive Behavioural Therapy, Physical Exercise, Placebo control
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 3 countries.

Kristine SirevågSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway. kristine.sirevag@solli.no.ORCID http://orcid.org/0000-0002-2349-2306
S H StavestrandSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway.
T SjøbøSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway.
T B EndalSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway.
H M NordahlDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, NO-7030, Norway.
E AnderssonThe Swedish School of Sport and Health Sciences, GIH, Stockholm, 5626 SE-114 86, box, Sweden.
I H NordhusDepartment of Clinical Psychology, University of Bergen, P.O. Box 7800, Bergen, NO-5020, Norway.
Å RekdalSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway.
K SpechtFaculty of humanities, social sciences and education, UiT The Arctic University of Norway, Tromsø, Norway.
Å HammarDepartment of Biological and Medical Psychology, University of Bergen, P.O. Box 7807, Bergen, NO- 5020, Norway.
A HalmøyDepartment of Psychiatry, Haukeland University Hospital, Kronstad DPS, P.O. Box 1400, Bergen, NO- 5021, Norway.
J MohlmanDepartment of Psychology, William Paterson University, 300 Pomton Road, Wayne, NJ, 07470, USA.
H HjelmervikSchool of Health Sciences, Kristiania University College, Kalfarveien 78c, Bergen, 5022, Norway.
J F ThayerDepartment of Psychological Science, The University of California, Irvine, 4201 Social and Behavioral Sciences Gateway, Irvine, CA, 92697, USA.
A HovlandSolli DPS, Osvegen 15 Nesttun, 5228, Bergen, Norway.
Bergen Kommune · NOHaukeland University Hospital · NOHøyskolen Kristiania · NOKarolinska Institutet · SENorwegian University of Science and Technology · NOUniversity of Bergen · NOUniversity of California, Irvine · USUniversity of Oslo · NOWilliam Paterson University · US

Funding

Helse Vest Regionalt Helseføretak Helse Vest Regionalt Helseføretak
6 · The paper itself

Abstract

backgroundGeneralised anxiety disorder (GAD) is a frequent and severe disorder among older adults. For older adults with GAD the effect of the recommended treatment, cognitive behaviour therapy (CBT), is reduced. Physical exercise (PE) may enhance the effect of CBT by improving cognitive function and increasing levels of brain-derived neurotrophic factor (BDNF), a predictor of the effect of CBT in patients with anxiety. The aim of the study was to assess the feasibility of a randomized controlled trial (RCT) investigating treatment effect of the combination of CBT and PE for GAD in a sample of older adults, including procedures for assessment and treatment.

methodsFour participants aged 62-70 years (M = 65.5, SD = 3.2) with a primary diagnosis of GAD were included. Participants received 15 weeks of PE in combination with 10 weeks of CBT. Participants completed self-report measures, and clinical, biological, physiological and neuropsychological tests at pre-, interim- and post-treatment.

resultsProcedures, protocols, and results are presented. One participant dropped out during treatment. For the three participants completing, the total adherence to PE and CBT was 80% and 100%, respectively. An independent assessor concluded that the completers no longer fulfilled the criteria for GAD after treatment. Changes in self-report measures suggest symptom reduction related to anxiety and worry. The sample is considered representative for the target population.

conclusionsThe results indicate that combining CBT and PE for older adults with GAD is feasible, and that the procedures and tests are suitable and manageable for the current sample.

trial registrationClinicalTrials.gov, NCT02690441. Registered on 24 February 2016, https://clinicaltrials.gov/ct2/show/NCT02690441 .

Indexed as

CBTCognitive behaviour therapyFeasibility studyGADGeneralised anxiety disorderOlder adultsPhysical exercise

Identifiers

PMID37468978
PMCPMC10357630
OpenAlexW4384820829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.