Evidence map›Paper›PMID 37468645›Full record

Trial reportEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2024

A prospective randomized controlled study of hamstring and bone-free quadriceps tendons autografts in arthroscopic ACL reconstruction.

Neset Tang, Murat Eren, Tahsin Gurpinar, Yusuf Ozturkmen

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06636045 (Effect of Blood Flow Restriction), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06636045 enrolling by invitationnot on this map

Effect of Blood Flow Restriction (BFR) on Rehabilitation Protocols Following Anterior Cruciate Ligament Reconstruction (ACLR) With Quadricep Autograft

Typeobservational_patient_registrySponsorUniversity of Kansas Medical CenterRan2024 to 2027Enrolled40ConditionsAutografts, Blood Flow Restriction Therapy, Rehabilitation Outcome, Quadriceps Muscle StrengthArmsNot applicable- observational study
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neset TangDepartment of Orthopedics and Traumatology, Istanbul Bakirkoy Training and Research Hospital, Tevfik Saglam St. Number 11, 34147, Bakirkoy/Istanbul, Turkey. nesettang@gmail.com.ORCID http://orcid.org/0000-0001-5045-8958
Murat ErenDepartment of Orthopedics and Traumatology, Istanbul Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7333-9430
Tahsin GurpinarJoondalup Orthopaedic Group, Joondalup, WA, Australia.ORCID http://orcid.org/0000-0002-8194-6492
Yusuf OzturkmenDepartment of Orthopedics and Traumatology, Istanbul Training and Research Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-2199-2411

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnterior cruciate ligament (ACL) reconstruction is one of the most common surgical procedures worldwide. However, the ideal graft source is still debatable. This study compared hamstring (HT) and bone-free quadriceps (QT) tendon autografts in terms of muscle strength and patient-reported outcomes.

methodsBetween June 2018 and December 2019, 46 patients were enrolled in the study and randomly assigned to one of two groups for the ACL reconstruction surgery-the HT autograft group or the QT autograft group. An experienced examiner performed preoperative and postoperative examinations. The HUMAC NORM isokinetic machine (Computer Sports Medicine International-CSMI, 2004) was used to assess flexor and extensor thigh muscle strength. Both groups received the same surgical technique and fixation method. All patients were examined after three, six, nine, and 12 months. The final evaluations were performed at the 24-month follow-up. Patients' scores on the International Knee Documentation Committee (IKDC) evaluation form and the Lysholm Knee Scoring Scale were used to evaluate patient-reported outcomes. The two groups were also compared in terms of postoperative complications and activity levels.

resultsThe difference between preoperative and postoperative knee flexor peak torques (FPT) was lower in the QT group than in the HT group. The average difference between preoperative and postoperative knee extensor peak torque (EPT) was higher in the QT group than in the HT group. As a result, the HT group had a lower postoperative H/Q ratio (flexor strength normalized to body mass divided by extensor strength normalized to body mass) than the QT group (p < 0.001). The mean IKDC scores for the HT and QT groups were 90.13 ± 6.99 and 87.12 ± 6.61, respectively. The scores of the two groups postoperatively were close, and both groups showed significant improvement. The average graft size in the QT group was significantly greater than that in the HT group. Saphenous nerve palsy was the most common complication in the HT group (22%). Thigh hematomas were observed in two patients in the QT group and required urgent intervention (12%).

conclusionAfter ACL reconstruction, we found a significant decrease in strength at the donor sites in both techniques, with similar patient-reported measures and stability outcomes. The H/Q strength ratio was higher in the QT group postoperatively, which may have a protective effect on the reconstructed ligament. Level of Evidence I It is a randomized controlled trial.

Indexed as

Anterior Cruciate Ligament InjuriesHamstring TendonsAutograftsHumansMuscle StrengthProspective StudiesQuadriceps MuscleTendonsTransplantation, AutologousACLHamstring tendonKnee injuryQuadriceps tendonReconstruction

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.