Evidence map›Paper›PMID 37468629›Full record

ArticleNature2023

Extreme dynamics in a biomolecular condensate.

Nicola Galvanetto, Miloš T Ivanović, Aritra Chowdhury, Andrea Sottini, Mark F Nüesch, Daniel Nettels, Robert B Best, Benjamin Schuler

Open access · greenAbstract read
In one paragraph

Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 191 papers.

0numbers the graph read from it
0cells of the map it votes in
191citing papers in PubMed
50.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

191 citing papers in PubMed, 329 citations in OpenAlex.

  1. Review
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  7. Review
  8. Current Challenges of Transcription Compartmentalization Research.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  9. Article
  10. Article
  11. The exchange dynamics of client molecules in biomolecular condensates.bioRxiv : the preprint server for biology · 2026
    Article
  12. Single-Molecule Dwell Times in Biomolecular Condensates.bioRxiv : the preprint server for biology · 2026
    Article
  13. Article
  14. Article
  15. Distinguishing near- versus off-critical phase behaviors of intrinsically disordered proteins.Reports on progress in physics. Physical Society (Great Britain) · 2026
    Article
  16. Review
  17. Article
  18. The Polymers of Life: Exploring Cellular Function Through Polymer Concepts.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  19. Article
  20. Article

131 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nicola Galvanetto *Department of Biochemistry, University of Zurich, Zurich, Switzerland. n.galvanetto@bioc.uzh.ch.ORCID 0000-0002-0408-1747
Miloš T Ivanović *Department of Biochemistry, University of Zurich, Zurich, Switzerland. m.ivanovic@bioc.uzh.ch.ORCID 0000-0003-3164-9411
Aritra ChowdhuryDepartment of Biochemistry, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-0579-292X
Andrea SottiniDepartment of Biochemistry, University of Zurich, Zurich, Switzerland.ORCID 0000-0001-8014-5987
Mark F NüeschDepartment of Biochemistry, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-8797-5470
Daniel NettelsDepartment of Biochemistry, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-3872-4955
Robert B BestLaboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA. robert.best2@nih.gov.ORCID 0000-0002-7893-3543
Benjamin SchulerDepartment of Biochemistry, University of Zurich, Zurich, Switzerland. schuler@bioc.uzh.ch.ORCID 0000-0002-5970-4251
University of Zurich · CHNational Institutes of Health · US

Funding

Understanding protein folding, evolution and function via molecular simulationZIADK075104 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BEST, ROBERT · 2013 to 2025
$13.7M
Intramural NIH HHS ZIA DK075104
6 · The paper itself

Abstract

Proteins and nucleic acids can phase-separate in the cell to form concentrated biomolecular condensates

Indexed as

Biomolecular CondensatesHumansIntrinsically Disordered ProteinsMolecular Dynamics SimulationSingle Molecule ImagingTime FactorsViscosityWaterIntrinsically Disordered ProteinsWater

Identifiers

PMID37468629
PMCPMC11508043
OpenAlexW4384819032

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.