ArticleNature2023
A spatially resolved timeline of the human maternal-fetal interface.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed, 1 pooled it
44.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
107 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.
- Multi-ancestry genome-wide association study of severe pregnancy nausea and vomiting.Nature genetics · 2026Pooled it
- Preconception sleep, pregnancy loss, and adverse pregnancy outcomes among women with a history of pregnancy loss.Human reproduction (Oxford, England) · 2025Trial
- Gene regulation at the early human maternal-fetal interface.Nature reviews. Genetics · 2026Review
- Structural Control of Stromal-Immune Coupling by COL24A1 Underlies Pregnancy Maintenance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Spatial Logic and Evolutionary Innovation in Human Placentation.bioRxiv : the preprint server for biology · 2026Article
- Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight.Experimental physiology · 2026Review
- HuBMAP Data Portal: a resource for multimodal spatial and single-cell data of healthy human tissues.ArXiv · 2026Article
- Toxoplasma gondii infection reduces CD59 expression through downregulation of JAK2/STAT3 signaling axis to enhance decidual NK cell cytotoxicity via the RAS/MAPK pathway.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Maternal NKG2D-mediated immune activation shapes fetal neural development.Molecular psychiatry · 2026Article
- EVT-Derived Migrasomes Provide Mechanistic Insights Into Antiphospholipid Syndrome-Associated Recurrent Miscarriage.American journal of reproductive immunology (New York, N.Y. : 1989) · 2026Article
- Spatially resolved fetal and maternal cell contributions to severe preeclampsia across gestation.Science advances · 2026Article
- From Adaptive Resilience to Catastrophic Systems Collapse: Endothelial Entropy, Ferroptotic Propagation, and the Maternal Point of No Return in Emergency Peripartum Hysterectomy.International journal of molecular sciences · 2026Review
- The pro-inflammatory cytokines IFN-α and TNF-α inhibit organoid-derived extravillous trophoblast invasion.iScience · 2026Article
- CD36: bridging metabolism, inflammation, and reproduction.npj metabolic health and disease · 2026Review
- Remodeling lesions locate at sites of strong extravillous trophoblast invasion and are associated with neutrophil presence in the human first-trimester decidua.Human reproduction (Oxford, England) · 2026Article
- Trophoblast aging driven by IL33 deficiency elevates recurrent pregnancy loss risk through SNAP29 lactylation-mediated autophagy impairment.Autophagy · 2026Article
- Maternal-Fetal Crosstalk in Cardiovascular Programming: Linking the Intrauterine Environment to Lifelong Disease Risk.Journal of cardiovascular development and disease · 2026Review
- Uterine natural killer cell-mediated immune imbalance impairs uterine vascular remodeling and contributes to adverse pregnancy outcomes in dengue virus-infected mice.Microbiology spectrum · 2026Article
- Genetic survey of biomarkers at early and mid-pregnancy identifies pregnancy-specialized immune regulation.PLoS genetics · 2026Article
- STEER: decoupling kinetics with Spatial-Temporal Explainable Expert model for RNA velocity inference.National science review · 2026Article
47 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors at 7 institutions in 2 countries.
Shirley Greenbaum *Department of Pathology, Stanford University, Stanford, CA, USA. greenbaumsh@gmail.com.ORCID 0000-0002-0680-7652
Inna Averbukh *Department of Pathology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1863-205X
Erin Soon *Department of Pathology, Stanford University, Stanford, CA, USA.
Gabrielle RizzutoDepartment of Pathology, University of Californica San Francisco, San Francisco, CA, USA.ORCID 0000-0003-3052-0253
Alex BaranskiDepartment of Pathology, Stanford University, Stanford, CA, USA.
Noah F GreenwaldDepartment of Pathology, Stanford University, Stanford, CA, USA.ORCID 0000-0002-7836-4379
Adam KagelDepartment of Pathology, Stanford University, Stanford, CA, USA.
Marc BosseDepartment of Pathology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-4912-8059
Eleni G JaswaDepartment of Obstetrics Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA, USA.
Zumana KhairDepartment of Pathology, Stanford University, Stanford, CA, USA.
Shirley KwokDepartment of Pathology, Stanford University, Stanford, CA, USA.
Shiri WarshawskyDepartment of Pathology, Stanford University, Stanford, CA, USA.
Hadeesha PiyadasaDepartment of Pathology, Stanford University, Stanford, CA, USA.
Mako GoldstonDepartment of Pathology, Stanford University, Stanford, CA, USA.
Angie SpenceDepartment of Pathology, Stanford University, Stanford, CA, USA.
Geneva MillerDivision of Biology and Bioengineering, California Institute of Technology, Pasadena, CA, USA.
Morgan SchwartzDivision of Biology and Bioengineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-8131-9125
Will GrafDivision of Biology and Bioengineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0002-4264-9479
David Van ValenDivision of Biology and Bioengineering, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-7534-7621
Virginia D WinnDepartment of Obstetrics and Gynecology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-1136-2907
Travis HollmannDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Leeat KerenDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-6799-6303
Matt van de RijnDepartment of Pathology, Stanford University, Stanford, CA, USA.
Michael AngeloDepartment of Pathology, Stanford University, Stanford, CA, USA. mangelo0@stanford.edu.ORCID 0000-0003-1531-5067
Stanford University · USCalifornia Institute of Technology · USUniversity of California, San Francisco · USHadassah Medical Center · ILMemorial Sloan Kettering Cancer Center · USStanford Medicine · USWeizmann Institute of Science · IL
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MStanford Cancer Immune Monitoring and Analysis Center (CIMAC)U24CA224309 · NCI · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Holden T. Maecker · 2017 to 2026
$19.9MThe Bone Marrow Multi-modal Imaging CoreU54HL165445 · NHLBI · STANFORD UNIVERSITY · PI ANGELO, ROBERT MICHAEL, BENDALL, SEAN CURTIS · 2022 to 2025
$5.9MMaternal T cell recognition of placental antigenK08AI137209 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RIZZUTO, GABRIELLE A · 2018 to 2022
$1.0MNCI NIH HHS P30 CA008748NCI NIH HHS U24 CA224309NHLBI NIH HHS U54 HL165445NIAID NIH HHS K08 AI137209
Abstract
Beginning in the first trimester, fetally derived extravillous trophoblasts (EVTs) invade the uterus and remodel its spiral arteries, transforming them into large, dilated blood vessels. Several mechanisms have been proposed to explain how EVTs coordinate with the maternal decidua to promote a tissue microenvironment conducive to spiral artery remodelling (SAR)
Indexed as
Maternal-Fetal ExchangeTrophoblastsUterusArteriesCD163 AntigenDatasets as TopicDeciduaFemaleGalectinsGene Expression ProfilingGestational AgeHepatitis A Virus Cellular Receptor 2HumansIndoleamine-Pyrrole 2,3,-DioxygenaseMembrane GlycoproteinsPregnancyCD163 AntigenGalectinsHAVCR2 protein, humanHepatitis A Virus Cellular Receptor 2IDO1 protein, humanIndoleamine-Pyrrole 2,3,-DioxygenaseLGALS9 protein, humanMembrane GlycoproteinsMRC1 protein, humanReceptors, Immunologic
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.