Evidence map›Paper›PMID 37468502›Full record

ArticleNature communications2023

Biodegradable polyphosphoester micelles act as both background-free

Olga Koshkina, Timo Rheinberger, Vera Flocke, Anton Windfelder, Pascal Bouvain, Naomi M Hamelmann, Jos M J Paulusse, Hubert Gojzewski, Ulrich Flögel, Frederik R Wurm

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Bypassing Heteronuclear MRI: Metal-Free Organosilicon Nanotracers for Background-Free HotspotAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Imaging of Thromboinflammation by MultispectralInternational journal of molecular sciences · 2025
    Review
  9. Review
  10. MRI detection of free-contrast agent nanoparticles.Magnetic resonance in medicine · 2025
    Article
  11. Article
  12. Article
  13. Review
  14. Real-timeCommunications chemistry · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Olga Koshkina *Sustainable Polymer Chemistry Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands. o.koshkina@utwente.nl.ORCID 0000-0002-1202-6465
Timo Rheinberger *Sustainable Polymer Chemistry Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.ORCID 0000-0001-8958-7677
Vera FlockeDepartment of Molecular Cardiology, Experimental Cardiovascular Imaging, Heinrich Heine University, Düsseldorf, Germany.
Anton WindfelderDepartment of Bioresources, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Giessen, Germany.ORCID 0000-0002-2611-8213
Pascal BouvainDepartment of Molecular Cardiology, Experimental Cardiovascular Imaging, Heinrich Heine University, Düsseldorf, Germany.ORCID 0000-0002-9116-1330
Naomi M HamelmannBiomolecular Nanotechnology Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, University of Twente, Enschede, The Netherlands.ORCID 0000-0002-7126-4818
Jos M J PaulusseBiomolecular Nanotechnology Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, University of Twente, Enschede, The Netherlands.ORCID 0000-0003-0697-7202
Hubert GojzewskiSustainable Polymer Chemistry Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands.
Ulrich FlögelDepartment of Molecular Cardiology, Experimental Cardiovascular Imaging, Heinrich Heine University, Düsseldorf, Germany. floegel@uni-duesseldorf.de.ORCID 0000-0001-7181-4392
Frederik R WurmSustainable Polymer Chemistry Group, Department of Molecules and Materials, MESA+ Institute of Nanotechnology, Faculty of Science and Technology, University of Twente, Enschede, The Netherlands. frederik.wurm@utwente.nl.ORCID 0000-0002-6955-8489
University of Twente · NLHeinrich Heine University Düsseldorf · DEJustus-Liebig-Universität Gießen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In vivo monitoring of polymers is crucial for drug delivery and tissue regeneration. Magnetic resonance imaging (MRI) is a whole-body imaging technique, and heteronuclear MRI allows quantitative imaging. However, MRI agents can result in environmental pollution and organ accumulation. To address this, we introduce biocompatible and biodegradable polyphosphoesters, as MRI-traceable polymers using the

Indexed as

MicellesPolymersDrug CarriersDrug Delivery SystemsMagnetic Resonance ImagingDrug CarriersMicellesPolymers

Identifiers

PMID37468502
PMCPMC10356825
OpenAlexW4384818172

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.