ArticleNature communications2023
Identification of a deep-branching thermophilic clade sheds light on early bacterial evolution.
Article in Nature communications, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Microbial Distributions Across Wide-Ranging Temperature Gradients of Hot Springs in Thailand: A Review of 35 Years of Research on Hot Spring-Associated Microorganisms.Environmental microbiology reports · 2026Review
- Thermophilic bacteria of the Arabian Gulf and their emerging biotechnological applications: current insights and future prospects.Frontiers in microbiology · 2026Review
- A genomic view of Earth's biomes.Nature reviews. Genetics · 2026Review
- Discovering rare thermophilic Parageobacillus caldoxylosilyticus from hot spring with early plastic-degrading potential revealed from bioassays and gene annotation studies.Folia microbiologica · 2025Article
- Scaling DNA synthesis with a microchip-based massively parallel synthesis system.Nature biotechnology · 2025Article
- Integrated Proteomic and Molecular Identification of ThermophilicLife (Basel, Switzerland) · 2025Article
- A metagenomic perspective on the microbial prokaryotic genome census.Science advances · 2025Article
- Benchmarking and optimizing qualitative and quantitative pipelines in environmental metatranscriptomics using mixture controlling experiments.ISME communications · 2025Article
- Comparative genomic analysis of thermophilic fungi reveals convergent evolutionary adaptations and gene losses.Communications biology · 2024Article
- Covariation of hot spring geochemistry with microbial genomic diversity, function, and evolution.Nature communications · 2024Article
- Hot springs viruses at Yellowstone National Park have ancient origins and are adapted to thermophilic hosts.Communications biology · 2024Article
- Mapping Geological Events and Nitrogen Fixation Evolution Onto the Timetree of the Evolution of Nitrogen-Fixation Genes.Molecular biology and evolution · 2024Article
- Leveraging genomic information to predict environmental preferences of bacteria.The ISME journal · 2024Review
- Bacterial diversity along the geothermal gradients: insights from the high-altitude Himalayan hot spring habitats of Sikkim.Current research in microbial sciences · 2024Article
- Effect of Fermented Concentrate on Ruminal Fermentation, Ruminal and Fecal Microbiome, and Growth Performance of Beef Cattle.Animals : an open access journal from MDPI · 2023Article
- Towards applications of genome-scale metabolic model-based approaches in designing synthetic microbial communities.Quantitative biology (Beijing, China) · 2023Review
- Proteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria.Nature communications · 2022Article
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It has been proposed that early bacteria, or even the last universal common ancestor of all cells, were thermophilic. However, research on the origin and evolution of thermophily is hampered by the difficulties associated with the isolation of deep-branching thermophilic microorganisms in pure culture. Here, we isolate a deep-branching thermophilic bacterium from a deep-sea hydrothermal vent, using a two-step cultivation strategy ("Subtraction-Suboptimal", StS) designed to isolate rare organisms. The bacterium, which we name Zhurongbacter thermophilus 3DAC, is a sulfur-reducing heterotroph that is phylogenetically related to Coprothermobacterota and other thermophilic bacterial groups, forming a clade that seems to represent a major, early-diverging bacterial lineage. The ancestor of this clade might be a thermophilic, strictly anaerobic, motile, hydrogen-dependent, and mixotrophic bacterium. Thus, our study provides insights into the early evolution of thermophilic bacteria.
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