Evidence map›Paper›PMID 37467726›Full record

ArticleCell reports. Medicine2023

Fast and low-dose medical imaging generation empowered by hybrid deep-learning and iterative reconstruction.

Shu Liao, Zhanhao Mo, Mengsu Zeng, Jiaojiao Wu, Yuning Gu, Guobin Li, Guotao Quan, Yang Lv, Lin Liu, Chun Yang and 12 more

Abstract read
In one paragraph

Article in Cell reports. Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
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  6. Review
  7. Article
  8. Review
  9. [Advances in low-dose cone-beam computed tomography image reconstruction methods based on deep learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
  10. Article
  11. Comparison ofEJNMMI physics · 2025
    Article
  12. Article
  13. Article
  14. State-of-the-Art Deep Learning CT Reconstruction Algorithms in Abdominal Imaging.Radiographics : a review publication of the Radiological Society of North America, Inc · 2024
    Review
  15. Article
  16. Review
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  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Shu LiaoDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Zhanhao MoDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Mengsu ZengDepartment of Radiology, Shanghai Institute of Medical Imaging, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Jiaojiao WuDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Yuning GuSchool of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China.
Guobin LiShanghai United Imaging Healthcare Co., Ltd., Shanghai 201800, China.
Guotao QuanShanghai United Imaging Healthcare Co., Ltd., Shanghai 201800, China.
Yang LvShanghai United Imaging Healthcare Co., Ltd., Shanghai 201800, China.
Lin LiuDepartment of Radiology, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
Chun YangDepartment of Radiology, Shanghai Institute of Medical Imaging, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Xinglie WangDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Xiaoqian HuangDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Yang ZhangDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Wenjing CaoShanghai United Imaging Healthcare Co., Ltd., Shanghai 201800, China.
Yun DongShanghai United Imaging Healthcare Co., Ltd., Shanghai 201800, China.
Ying WeiDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Qing ZhouDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Yongqin XiaoDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Yiqiang ZhanDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Xiang Sean ZhouDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China.
Feng ShiDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China. Electronic address: feng.shi@uii-ai.com.
Dinggang ShenDepartment of Research and Development, Shanghai United Imaging Intelligence Co., Ltd., Shanghai 200232, China; School of Biomedical Engineering, ShanghaiTech University, Shanghai 201210, China; Shanghai Clinical Research and Trial Center, Shanghai 200122, China. Electronic address: dinggang.shen@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fast and low-dose reconstructions of medical images are highly desired in clinical routines. We propose a hybrid deep-learning and iterative reconstruction (hybrid DL-IR) framework and apply it for fast magnetic resonance imaging (MRI), fast positron emission tomography (PET), and low-dose computed tomography (CT) image generation tasks. First, in a retrospective MRI study (6,066 cases), we demonstrate its capability of handling 3- to 10-fold under-sampled MR data, enabling organ-level coverage with only 10- to 100-s scan time; second, a low-dose CT study (142 cases) shows that our framework can successfully alleviate the noise and streak artifacts in scans performed with only 10% radiation dose (0.61 mGy); and last, a fast whole-body PET study (131 cases) allows us to faithfully reconstruct tumor-induced lesions, including small ones (<4 mm), from 2- to 4-fold-accelerated PET acquisition (30-60 s/bp). This study offers a promising avenue for accurate and high-quality image reconstruction with broad clinical value.

Indexed as

Deep LearningImage Processing, Computer-AssistedPositron-Emission TomographyRetrospective StudiesTomography, X-Ray Computeddeep learningfast MRIfast PETiterative reconstructionlow-dose CT

Identifiers

PMID37467726
PMCPMC10394257

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.