Evidence map›Paper›PMID 37467700›Full record

ArticleJournal of neuroimmunology2023

MOG-specific T cell response amplified in para- and post-SAR-CoV-2 infection in myelin oligodendrocyte glycoprotein antibody-associated disease.

Qi Wu, Smathorn Thakolwiboon, Ahya S Ali, Qin Wang, Deanna Dwyer, David A Fox, Yang Mao-Draayer

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroimmunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Qi WuDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA; Autoimmunity Center of Excellence, 4015 A. Alfred Taubman Biomedical Sciences Research Building 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: qiw@med.umich.edu.
Smathorn ThakolwiboonDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA; Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: Thakolwiboon.Smathorn@mayo.edu.
Ahya S AliDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: ahyasali@umich.edu.
Qin WangDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA; Autoimmunity Center of Excellence, 4015 A. Alfred Taubman Biomedical Sciences Research Building 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA. Electronic address: qinwang@med.umich.edu.
Deanna DwyerDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA. Electronic address: ddeanna@umich.edu.
David A FoxAutoimmunity Center of Excellence, 4015 A. Alfred Taubman Biomedical Sciences Research Building 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA; Division of Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: dfox@med.umich.edu.
Yang Mao-DraayerDepartment of Neurology, University of Michigan, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA; Autoimmunity Center of Excellence, 4015 A. Alfred Taubman Biomedical Sciences Research Building 109 Zina Pitcher Place, Ann Arbor, MI 48109, USA; Michigan Institute for Neurological Disorders, USA. Electronic address: yangmaodraayer@gmail.com.
University of Michigan–Ann Arbor · USA. Alfred Taubman Health Care Center · US

Funding

CD24 Targeting for Multiple Sclerosis: a First-In-Human Phase I StudyR01NS080821 · NINDS · ONCOIMMUNE, INC. · PI LIU, YANG · 2013 to 2014
$1.1M
University of Michigan Clinical Autoimmunity Center of ExcellenceUM1AI144298 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FOX, DAVID ALAN, KHANNA, DINESH · 2019 to 2023
$546k
University of Michigan Autoimmunity Center of Excellence, Clinical Research ProgrUM1AI110557 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FOX, DAVID ALAN · 2014 to 2018
$543k
NIAID NIH HHS UM1 AI110557NIAID NIH HHS UM1 AI144298NINDS NIH HHS R01 NS080821
6 · The paper itself

Abstract

We describe clinical characteristics and deep immunophenotypes in two patients with myelin-oligodendrocyte-glycoprotein (MOG)-antibody-associated-disease after COVID-19. The para-COVID case was a 74-year-old man who developed optic neuritis two days after COVID-19. Immunological assays revealed reduced absolute CD8

Indexed as

COVID-19Myelin-Oligodendrocyte GlycoproteinOptic NeuritisAgedAutoantibodiesCD8-Positive T-LymphocytesHumansMaleMiddle AgedSARS-CoV-2AutoantibodiesMyelin-Oligodendrocyte GlycoproteinCOVID-19MOGADMyelin oligodendrocyte glycoprotein antibody-associated diseaseOptic neuritisSAR-CoV-2

Identifiers

PMID37467700
PMCPMC11392592
OpenAlexW4383485182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.