Evidence map›Paper›PMID 37467460›Full record

ArticleACS applied materials & interfaces2023

Semiconducting Polymer Nanoporous Thin Films as a Tool to Regulate Intracellular ROS Balance in Endothelial Cells.

Miryam Criado-Gonzalez, Luca Bondi, Camilla Marzuoli, Edgar Gutierrez-Fernandez, Gabriele Tullii, Carlotta Ronchi, Elena Gabirondo, Haritz Sardon, Stefania Rapino, Marco Malferrari and 3 more

Open access · hybridAbstract read
In one paragraph

Article in ACS applied materials & interfaces, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Miryam Criado-GonzalezPOLYMAT, University of the Basque Country UPV/EHU, Paseo Manuel de Lardizabal 3, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-5502-892X
Luca BondiDepartment of Physics and Astronomy, University of Bologna, Viale Carlo Berti Pichat 6/2, 40127 Bologna, Italy.
Camilla MarzuoliCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Via Raffaele Rubattino 81, 20134 Milano, Italy.
Edgar Gutierrez-FernandezPOLYMAT, University of the Basque Country UPV/EHU, Paseo Manuel de Lardizabal 3, 20018 Donostia-San Sebastián, Spain.
Gabriele TulliiCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Via Raffaele Rubattino 81, 20134 Milano, Italy.ORCID 0000-0002-6595-3449
Carlotta RonchiCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Via Raffaele Rubattino 81, 20134 Milano, Italy.
Elena GabirondoPOLYMAT, University of the Basque Country UPV/EHU, Paseo Manuel de Lardizabal 3, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0001-9635-0790
Haritz SardonPOLYMAT, University of the Basque Country UPV/EHU, Paseo Manuel de Lardizabal 3, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-6268-0916
Stefania RapinoDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.ORCID 0000-0001-6913-0119
Marco MalferrariDepartment of Chemistry "Giacomo Ciamician", University of Bologna, 40126 Bologna, Italy.
Tobias CramerDepartment of Physics and Astronomy, University of Bologna, Viale Carlo Berti Pichat 6/2, 40127 Bologna, Italy.ORCID 0000-0002-5993-3388
Maria Rosa AntognazzaCenter for Nano Science and Technology@PoliMi, Istituto Italiano di Tecnologia, Via Raffaele Rubattino 81, 20134 Milano, Italy.ORCID 0000-0003-4599-2384
David MecerreyesPOLYMAT, University of the Basque Country UPV/EHU, Paseo Manuel de Lardizabal 3, 20018 Donostia-San Sebastián, Spain.ORCID 0000-0002-0788-7156
Italian Institute of Technology · ITUniversity of Bologna · ITUniversity of the Basque Country · ESIkerbasque · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The design of soft and nanometer-scale photoelectrodes able to stimulate and promote the intracellular concentration of reactive oxygen species (ROS) is searched for redox medicine applications. In this work, we show semiconducting polymer porous thin films with an enhanced photoelectrochemical generation of ROS in human umbilical vein endothelial cells (HUVECs). To achieve that aim, we synthesized graft copolymers, made of poly(3-hexylthiophene) (P3HT) and degradable poly(lactic acid) (PLA) segments, P3HT-

Indexed as

NanoporesPolymersEndothelial CellsHumansPolyestersReactive Oxygen SpeciesPolyestersPolymersReactive Oxygen Speciesbiophotonicscell optical modulationpoly(3-hexylthiophene)porous filmsreactive oxygen species (ROS)

Identifiers

PMID37467460
PMCPMC10401575
OpenAlexW4384818142

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.