Evidence map›Paper›PMID 37467340›Full record

ArticleScience advances2023

Nonsteroidal anti-inflammatory drugs sensitize epithelial cells to

Joshua Soto Ocaña, Nile U Bayard, Jessica L Hart, Audrey K Thomas, Emma E Furth, D Borden Lacy, David M Aronoff, Joseph P Zackular

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Colonic epithelial regeneration shapes susceptibility tobioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Pharmacological reduction of neutrophil infiltration reducesbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Gene Expression Dysregulation in Whole Blood of Patients withInternational journal of molecular sciences · 2024
    Article
  11. A multivalent mRNA-LNP vaccine protects againstScience (New York, N.Y.) · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Joshua Soto OcañaDivision of Protective Immunity, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-8898-6630
Nile U BayardDivision of Protective Immunity, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Jessica L HartDivision of Protective Immunity, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0001-5542-0860
Audrey K ThomasDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
Emma E FurthDepartment of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
D Borden LacyDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.ORCID 0000-0003-2273-8121
David M AronoffDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.ORCID 0000-0003-4587-6121
Joseph P ZackularDivision of Protective Immunity, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.ORCID 0000-0002-3228-3055
Children's Hospital of Philadelphia · USVanderbilt University Medical Center · USIndiana University School of MedicineUniversity of Pennsylvania · US

Funding

Translational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9M
Structural Mechanisms of Clostridioides difficile pathogenesisR37AI095755 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Dana Borden Lacy · 2021 to 2026
$3.2M
Molecular interactions in the gut microbiota during early life colonization and perturbationR35GM138369 · NIGMS · CHILDREN'S HOSP OF PHILADELPHIA · PI Joseph Paul Zackular · 2020 to 2026
$2.7M
The Impact of Vancomycin-Resistant Entercoccus on Clostridium difficile InfectionK22AI137220 · NIAID · CHILDREN'S HOSP OF PHILADELPHIA · PI ZACKULAR, JOSEPH PAUL · 2019 to 2020
$270k
FACTORS AFFECTING TRANSMISSION OF LAC VIRUSF32AI007220 · NIAID · UNIVERSITY OF NOTRE DAME · PI HAWLEY, WILLIAM A · 1985 to 1986
–
BLRD VA I01 BX002943NIAID NIH HHS K22 AI137220NIAID NIH HHS K22AI7220NIAID NIH HHS R37 AI095755NIAID NIH HHS R37AI095755-12NIDDK NIH HHS P30 DK058404NIGMS NIH HHS R35 GM138369
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacterial ToxinsClostridioides difficileAnti-Inflammatory Agents, Non-SteroidalEcosystemEpithelial CellsAnti-Inflammatory Agents, Non-SteroidalBacterial Toxins

Identifiers

PMID37467340
PMCPMC10355836
OpenAlexW4384652036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.