Evidence map›Paper›PMID 37467285›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2023

Prostaglandin E

Lisa Z Fang, Victoria Linehan, Maria Licursi, Christian O Alberto, Jacob L Power, Matthew P Parsons, Michiru Hirasawa

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Systematic review: The gut microbiota as a link between colorectal cancer and obesity.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lisa Z FangDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.
Victoria LinehanDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.ORCID 0000-0002-5704-3488
Maria LicursiDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.
Christian O AlbertoDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.
Jacob L PowerDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.
Matthew P ParsonsDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.
Michiru HirasawaDivision of Biomedical Sciences, Faculty of Medicine, Memorial University, St. John's A1B 3V6, Canada.ORCID 0000-0002-2491-8102
Memorial University of Newfoundland · CA

Funding

CIHR PJT-153173
6 · The paper itself

Abstract

Hypothalamic inflammation reduces appetite and body weight during inflammatory diseases, while promoting weight gain when induced by high-fat diet (HFD). How hypothalamic inflammation can induce opposite energy balance outcomes remains unclear. We found that prostaglandin E

Indexed as

Fatty LiverObesityAnimalsDiet, High-FatFemaleHypothalamic HormonesHypothalamusInflammationInflammation MediatorsMaleMelaninsMiceNeuronsPituitary HormonesProstaglandinsRatsHypothalamic HormonesInflammation Mediatorsmelanin-concentrating hormoneMelaninsPituitary HormonesProstaglandinsEP2 receptorhigh-fat diethypothalamusNa+/K+-ATPaseprostaglandin E2

Identifiers

PMID37467285
PMCPMC10401019
OpenAlexW4384819461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.