ArticleChemistry (Weinheim an der Bergstrasse, Germany)2023
Cobalt-Catalyzed Decarboxylative Allylations: Development and Mechanistic Studies.
Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Reductive coupling of allenyl/allyl carbonate with alkyne under dual cobalt-photoredox catalysis.Nature communications · 2024Article
- Transition metal-free decarboxylative olefination of carboxylic acid salts.Chemical science · 2024Article
- Cobalt-catalyzed decarboxylative difluoroalkylation of nitrophenylacetic acid salts.Chemical science · 2023Article
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Authors and funding
3 authors.
Funding
Abstract
In recent years, there has been a concerted drive to develop methods that are greener and more sustainable. Being an earth-abundant transition metal, cobalt offers an attractive substitute for commonly employed precious metal catalysts, though reactions engaging cobalt are still less developed. Herein, we report a method to achieve the decarboxylative allylation of nitrophenyl alkanes, nitroalkanes, and ketones employing cobalt. The reaction allows for the formation of various substituted allylated products in moderate-excellent yields with a broad scope. Additionally, the synthetic potential of the methodology is demonstrated by the transformation of products into versatile heterocyclic motifs. Mechanistic studies revealed an in situ activation of the Co(II)/dppBz precatalyst by the carboxylate salt to generate a Co(I)-species, which is presumed to be the active catalyst.
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Registered trials
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