ArticleQJM : monthly journal of the Association of Physicians2023
Frailty in younger adults in hospital.
Article in QJM : monthly journal of the Association of Physicians, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Association of frailty index with sarcopenia: Mediation analysis of triglyceride-glucose-related indices: a cross-sectional study.Medicine · 2026Article
- Prognostic value of nutritional and functional screening instruments for mortality in patients with hematologic malignancies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Identifying Key Predictors of Appropriate Discharge Destinations for Older Inpatients in Acute Care: Scoping Review.Interactive journal of medical research · 2026Review
- Frailty Modifies the Prognostic Effect of Age Among Older Adults With Acute Coronary Syndrome.Journal of the American Heart Association · 2026Observational
- Association between hospital frailty risk score, risk of sepsis and adverse outcomes across all adult ages.PloS one · 2026Article
- Article
- Identification of novel biomarkers and drug targets for frailty-related skeletal muscle aging: a multi-omics study.QJM : monthly journal of the Association of Physicians · 2025Article
- Association between alpha-1-acid glycoprotein and frailty in US females aged 20-49 years: analysis of NHANES data (2015-2023).Scientific reports · 2025Article
- Consumers' Perspectives on the Design of a New Digital Frailty Education Course, 'Focus on Frailty': A Qualitative Co-Design Study.Health expectations : an international journal of public participation in health care and health policy · 2025Article
- External validation of the TFC (triage frailty and comorbidity) tool: a prospective observational study.Internal and emergency medicine · 2025Observational
- Frailty and body composition predict adverse outcomes after emergency general surgery admission: a multicentre observational cohort study.Annals of the Royal College of Surgeons of England · 2025Observational
- Assessing the utility of frailty scores in triage: a comparative study of validated scales.Internal and emergency medicine · 2025Observational
- Development of an emergency department triage tool to predict admission or discharge for older adults.International journal of emergency medicine · 2025Article
- Age does not improve the predictive ability of the Hospital Frailty Risk Score for length of stay.PloS one · 2025Article
- Using the Hospital Frailty Risk Score to predict length of stay across all adult ages.PloS one · 2025Article
- Daily consumption of specific categories of fruit and vegetables negatively correlated with frailty: findings from the US National Health and Nutrition Examination Survey.Nutrition research and practice · 2024Article
- Development and validation of a nomogram for assessing comorbidity and frailty in triage: a multicentre observational study.Internal and emergency medicine · 2024Observational
- Predicting Outcomes in Frail Older Community-Dwellers in Western Australia: Results from the Community Assessment of Risk Screening and Treatment Strategies (CARTS) Programme.Healthcare (Basel, Switzerland) · 2024Article
- Frailty in an Adult Acute Hospital Population: Predictors, Prevalence, and Outcomes.International journal of environmental research and public health · 2024Article
- Association of the Tilburg Frailty Indicator with mortality, readmission, and healthcare contacts in adult patients with multimorbidity.Journal of multimorbidity and comorbidityArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEven though frailty has been extensively measured in the acute care setting, relatively little is known about the frailty of younger adult inpatients.
aimThis study aimed to measure frailty in a sample of hospitalized adults aged 18 years and over and to examine how frailty in younger adult inpatients differs from middle-aged and older adult inpatients.
designSecondary analyses of prospectively collected cohort data.
methodsResearch nurses assessed 910 patients at admission to four Australian hospitals using the interRAI Acute Care instrument. Comparison of frailty index (FI) scores and domains was conducted across three age groups: younger (18-49 years), middle-aged (50-69 years) and older adults (≥70 years). Multivariable logistic regression examined risk of prolonged length of stay and unfavourable discharge destination.
resultsYounger adults (n = 214; 23.5%) had a mean (SD) FI of 0.19 (0.10). Approximately 27% (n = 57) of younger adults were frail (FI > 0.25). Mood and behaviour, health symptoms and syndromes, nutrition and pain were the most frequently affected domains in younger adults and 50% had ≥3 comorbidities. Frailty increased the risk of long length of stay (odds ratio (OR) = 1.77, P < 0.001) but not the risk of an unfavourable discharge (OR = 1.40, P = 0.20) in younger adults.
conclusionsThis study showed that frailty is prevalent in younger patients admitted to acute care and is associated with adverse outcomes. This study was a critical first step towards establishing an understanding of frailty in younger hospitalized adults.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.