SynthesisClinical and experimental nephrology2023
The effect of renal replacement therapy on health-related quality of life in end-stage renal disease: a meta-analysis.
Synthesis in Clinical and experimental nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Impact of digital health technology-based nutritional interventions on the nutritional status of hemodialysis patients: a systematic review and meta-analysis.Frontiers in nutrition · 2025Pooled it
- Posttransplant diabetes mellitus (PTDM) frequency, risk factors, and outcomes: a single-center experience.BMC nephrology · 2025Observational
- Health Literacy and Emotional Management in Patients on Renal Replacement Therapy: A Mixed-Method Study Protocol.Healthcare (Basel, Switzerland) · 2025Article
- Home Dialysis Prediction Using Artificial Intelligence.Kidney medicine · 2025Article
- Deceased Kidney Donor Biomarkers: Relationship between Delayed Kidney Function and Graft Function Three Years after Transplantation.Diagnostics (Basel, Switzerland) · 2024Article
- Risk factors for lower renal compensation after nephrectomy: an analysis of living kidney donors in an Amazonian cohort.Jornal brasileiro de nefrologia · 2024Observational
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEnd-stage renal disease (ESRD) patients judge health-related quality of life (HRQoL) as an essential outcome. In meta-analysis studies, there is ongoing debate regarding the impact of renal replacement therapy (RRT) methods on HRQoL in ESRD patients. Hence, the main objective of this study was to examine the influence of RRT method utilization on HRQoL in individuals with ESRD. Additionally, the secondary objective was to explore the impact of RRT method use on HRQoL, considering various moderator variables.
methodsRRT methods called hemodialysis (HD), peritoneal dialysis (PD), home dialysis (HoD), and kidney transplantation (KT) are used to treat ESRD. HD was defined as in-center HD (ICHD) and home HD (HHD). HoD was defined as HHD and PD. The estimated Hedges' g were conducted by random effect meta-analysis.
resultsA total of 111 publications, including 50.151 patients, were included. KT was better at improving patients' HRQoL than other methods. PD was better at improving patients' HRQoL than HD. HoD was better at improving patients' HRQoL than ICHD. Sensitivity analyses yielded similar results. Publication bias was not tested. The subgroup and meta-regression analyses showed that the moderating variables had a statistically significant effect on the HRQoL of patients with ESRD.
conclusionFor the treatment of ESRD, either KT, PD, or HoD can be used in terms of HRQoL. We need to improve the factors affecting the HRQoL of ESRD patients undergoing HD and ICHD. Healthcare professionals should consider the factors that influence HRQoL and choose an RTT method for each ESRD patient.
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