Evidence map›Paper›PMID 37466716›Full record

SynthesisClinical oral investigations2023

Prevalence of postoperative pain after endodontic treatment using low and high concentrations of sodium hypochlorite: a systematic review and meta-analysis.

Rayssa Sabino-Silva, Ihan Vitor Cardoso, Filipe Colombo Vitali, Ana Maria Hecke Alves, Beatriz Dulcineia Mendes Souza, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia, Cleonice da Silveira Teixeira

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rayssa Sabino-SilvaDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Ihan Vitor CardosoDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Filipe Colombo VitaliDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Ana Maria Hecke AlvesDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Beatriz Dulcineia Mendes SouzaDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Eduardo Antunes BortoluzziDepartment of Diagnosis & Oral Health, School of Dentistry, University of Louisville, Louisville, KY, USA.
Lucas da Fonseca Roberti GarciaDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil.
Cleonice da Silveira TeixeiraDepartment of Dentistry, Federal University of Santa Catarina, Delfino Conti S/N, Trindade, Santa Catarina, 88040-370, Florianopolis, Brazil. cleonice.teixeira@ufsc.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the prevalence of postoperative pain after endodontic treatment using low (LC) and high (HC) concentrations of sodium hypochlorite (NaOCl). MATERIALS AND

methodsSix databases and the grey literature were searched to identify randomized clinical trials that evaluated postoperative pain after endodontic treatment using NaOCl. NaOCl concentrations were dichotomized into 'LC' (0.5% to 3%) and 'HC' (≥ 5%) and a proportion meta-analysis was applied to determine the postoperative pain prevalence: overall and according to pain intensity and postoperative time. The prevalence of patients using pain control medication was also determined. A significance level of 5% and a random effect model were applied for data analysis. Between-study heterogeneity was assessed by I

resultsTen studies were included in the review and eight in the meta-analysis. The overall prevalence of postoperative pain was 45% in LC and 39% in HC. The prevalence of pain in LC and HC after 24 h was 25% and 40%, respectively. After 48 h, the prevalence decreased to 10% in LC and 25% in HC. 'Absent pain' was the most prevalent score. The prevalence of patients who used medication was 9% in LC and 15% in HC. Three studies were classified as 'high RoB', five as 'low RoB', and two as 'some concerns'. The certainty of evidence was very low.

conclusionsThe overall prevalence of postoperative pain after endodontic treatment using LC and HC of NaOCl was 45% and 39%, respectively. CLINICAL RELEVANCE: Postoperative pain is common after endodontic treatment using NaOCl, but tends to decrease over time.

Indexed as

Root Canal IrrigantsSodium HypochloriteHumansPain ManagementPostoperative PainPrevalenceRoot Canal IrrigantsSodium HypochloriteEndodonticsIrrigating solutionPostoperative painSodium hypochloriteSystematic review

Identifiers

PMID37466716

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.