Evidence map›Paper›PMID 37466709›Full record

ArticleEuropean radiology2023

Efficacy and safety of microwave ablation for the treatment of multifocal versus unifocal T1N0M0 papillary thyroid carcinoma: a propensity-matched multicentre retrospective study.

Zhen-Long Zhao, Gang Dong, Shu-Rong Wang, Ying Liu, Jun-Feng He, Li-Li Shi, Jian-Qin Guo, Zhong-Hua Wang, Zhi-Bin Cong, Li-Hong Liu and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 1 country.

Zhen-Long Zhao *Department of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Gang Dong *Department of Ultrasound, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Shu-Rong WangDepartment of Ultrasound, Yantai Hospital of Shandong Wendeng Orthopaedics & Traumatology, Yantai, Shandong, China.
Ying LiuDepartment of Ultrasound, Yantai Hospital of Shandong Wendeng Orthopaedics & Traumatology, Yantai, Shandong, China.
Jun-Feng HeDepartment of Ultrasound, the First Affiliated Hospital of Baotou Medical College of Inner Mongolia University of Science and Technology, Baotou, Inner Mongolia, China.
Li-Li ShiDepartment of Ultrasound, Laixi Municipal Hospital, Laixi, Shandong, China.
Jian-Qin GuoDepartment of Interventional Ultrasound, The First Affiliated Hospital of Hainan Medical Univeristy, Haikou, Hainan, China.
Zhong-Hua WangDepartment of Special Inspection, Wendeng District People's Hospital, Weihai, Shandong, China.
Zhi-Bin CongDepartment of Electrodiagnosis, the Affiliated Hospital to Changchun University of Traditional Chinese Medicine, Changchun, Jilin, China.
Li-Hong LiuDepartment of Medical Ultrasound, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Bei-Bei YangDepartment of Medical Ultrasound, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, Shandong, China.
Chun-Ping QuDepartment of Special Inspection, Muping Zhongyi Hospital, Yantai, Shandong, China.
Ying WeiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Li-Li PengDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Yan LiDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Nai-Cong LuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Jie WuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China.
Ming-An YuDepartment of Interventional Medicine, China-Japan Friendship Hospital, Beijing, China. yma301@163.com.ORCID http://orcid.org/0000-0003-0797-4564
China-Japan Friendship Hospital · CNBinzhou Medical University · CNYantaishan Hospital · CNFirst Affiliated Hospital of Zhengzhou University · CNHainan Medical University · CNInner Mongolia University of Science and Technology · CNThe Affiliated Hospital to Changchun University of Chinese Medicine · CN

Funding

Beijing Engineering and Technology Research Center of Food Additives 2022-YJXBF-04-04National High Level Hospital Clinical Research Funding 2022-NHLHCRF-PY-07National Natural Science Foundation of China 62176268
6 · The paper itself

Abstract

objectivesMicrowave ablation (MWA) has been widely used for unifocal papillary thyroid carcinoma (U-PTC) and has recently been preliminarily used in multifocal papillary thyroid carcinoma (M-PTC). However, the efficacy and safety of MWA for M-PTC have not been investigated in large samples. The aim of the present study was to evaluate the efficacy and safety of MWA for M-PTC and compare them with MWA for U-PTC. MATERIALS AND

methodsThis retrospective multicentre study enrolled 504 patients (376 females) who underwent MWA for U-PTC (340 cases) or M-PTC (164 cases) from Jan 2015 to Dec 2020. The median age of the patients was 43 years (age range, 20-80 years). Propensity score matching (PSM) was used to balance the baseline characteristics between M-PTC group and U-PTC group. The tumour progression, tumour disappearance, and complication rates were compared between the two groups.

resultsThe complete ablation was achieved in all enrolled cases in one session. According to the statistical results, no significant differences were shown in tumour progression-free survival (p  = 0.29) or cumulative tumour progression rate (6.7% vs. 4.3%, p  = 0.33) between the M-PTC and U-PTC groups during the follow-up time. However, the tumour disappearance rate in the M-PTC group was lower in the U-PTC group (40.9% vs. 62.8%, p < 0.001), and tumour disappearance was slower in the M-PTC group (p < 0.001). The complication rate showed no significant difference (3.0% vs. 4.9%, p  = 0.571).

conclusionsMWA is an effective and safe treatment for selected patients with M-PTC, and the prognosis is similar to that of U-PTC. CLINICAL RELEVANCE STATEMENT: The present study provided evidence that compared with unifocal papillary thyroid cancer, microwave ablation could also treat multifocal T1N0M0 papillary thyroid cancer safely with similar clinical outcome, which could promote the application of minimally invasive treatment for papillary thyroid cancer. KEY

results• Microwave ablation for multifocal and unifocal T1N0M0 papillary thyroid carcinoma had similar tumour progression rates after propensity score matching (6.7% vs. 4.3%, p = 0.33). • The tumour disappearance rate in the multifocal group was lower than that in the unifocal group (40.9% vs. 62.8%, p < 0.001), and tumour disappearance was slower in the multifocal group (p < 0.001). • Tumour size, number, and location were not risk factors for tumour progression in the multifocal papillary thyroid cancer group.

Indexed as

Carcinoma, PapillaryThyroid NeoplasmsAdultAgedAged, 80 and overFemaleHumansMicrowavesMiddle AgedRetrospective StudiesThyroid Cancer, PapillaryTreatment OutcomeYoung AdultAblation techniquesPapillary thyroid cancerPropensity score

Identifiers

PMID37466709
OpenAlexW4384665231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.