Evidence map›Paper›PMID 37466666›Full record

ArticleParasitology research2023

Comparative evaluation of cell-mediated immune response in calves immunized with live-attenuated and killed Theileria annulata vaccines.

Muhammad Sajid Ramzan, Muhammad Suleman, Muhammad Imran Rashid, Haroon Akbar, Muhammad Avais

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Article in Parasitology research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Muhammad Sajid RamzanDepartment of Parasitology, University of Veterinary and Animal Sciences, Lahore, 54200, Pakistan.
Muhammad SulemanInstitute of Microbiology, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan. muhammad.suleman@uvas.edu.pk.
Muhammad Imran RashidDepartment of Parasitology, University of Veterinary and Animal Sciences, Lahore, 54200, Pakistan. imran.rashid@uvas.edu.pk.
Haroon AkbarDepartment of Parasitology, University of Veterinary and Animal Sciences, Lahore, 54200, Pakistan.
Muhammad AvaisDepartment of Veterinary Medicine, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan.
University of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tropical theileriosis is a tick-borne disease caused by the protozoan Theileria annulata and transmitted by numerous species of Ixodid ticks of the genus Hyalomma. The main clinical signs are fever, lymphadenopathy, and anemia responsible for heavy economic losses, including mortality, morbidity, vaccination failure, and treatment cost. Development of poor cell-mediated immunity (CMI) has been observed in the case of many bovine pathogens (bacteria, viruses, and parasites). Quantification of CMI is a prerequisite for evaluating vaccine efficacy against theileriosis caused by T. annulata. The current study evaluated the CMI in calves administered with two types of T. annulata vaccine (live attenuated and killed). We prepared a live attenuated T. annulata vaccine by attenuation in a rabbit model and also prepared killed vaccine from non-attenuated T. annulata. For the evaluation of immune response in experimental groups including control, 20 calves were divided into four different groups (A, B, C, and D). They were either inoculated subcutaneously with live rabbit-propagated-Theileria-infected RBCs (5 × 10

Indexed as

Cattle DiseasesIxodidaeProtozoan VaccinesTheileria annulataTheileriasisAnimalsCattleImmunity, CellularImmunizationRabbitsVaccines, InactivatedProtozoan VaccinesVaccines, InactivatedBovine theileriosisCD4 + T cellsCD8 + T cellsCell-mediated immunityKilled vaccineLive attenuated vaccineTheileria annulata

Identifiers

PMID37466666
OpenAlexW4384665297

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.