Evidence map›Paper›PMID 37466648›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2023

Ankylosing spondylitis PET imaging and quantifications via P2X7 receptor-targeting radioligand [

Shiyanjin Zhang, Yifan Qiu, Lihua Huang, Lei Bi, Yuanqing Guo, Ke You, Guolong Huang, Yuhan Wang, Hai Lu, Hongjun Jin and 1 more

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Shiyanjin Zhang *Department of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China.
Yifan Qiu *Guangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
Lihua Huang *Department of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China.
Lei BiGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
Yuanqing GuoDepartment of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China.
Ke YouDepartment of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China.
Guolong HuangGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
Yuhan WangDepartment of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China.
Hai LuDepartment of Spine Surgery, Sun Yat-Sen University Fifth Affiliated Hospital, Zhuhai, 519000, Guangdong Province, China. lvhai@mail.sysu.edu.cn.
Hongjun JinGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China. jinhj3@mail.sysu.edu.cn.ORCID 0000-0002-1522-1098
Hong ShanGuangdong Provincial Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, 519000, Guangdong Province, China.
Sun Yat-sen University · CN

Funding

Guangdong Provincial Basic and Applied Basic Research Fund Provincial Enterprise Joint Fund 2021A1515220004Key Realm R&D Program of Guangdong Province 2018B030337001National Natural Science Foundation of China 81871382National Natural Science Foundation of China 82150610508Special Fund Project for Science and Technology Innovation Strategy of Guangdong Province 0056/2021/AGJZhuhai City Innovation and Innovation Team Project ZH0406190031PWC
6 · The paper itself

Abstract

purposeAnkylosing spondylitis (AS) is a chronic inflammatory disease of the axial spine; however, the quantitative detection of inflammation in AS remains a challenge in clinical settings. We aimed to investigate the feasibility of using a specific P2X7R-targeting

methodsThe radioligand [

results[

conclusionThis study developed a novel P2X7R-targeting PET tracer [

Indexed as

Positron Emission Tomography Computed TomographyRadiopharmaceuticalsReceptors, Purinergic P2X7Spondylitis, AnkylosingAnimalsFluorine RadioisotopesLigandsMaleMiceFluorine-18Fluorine RadioisotopesLigandsRadiopharmaceuticalsReceptors, Purinergic P2X7Ankylosing spondylitis (AS)MacrophageMicro-PET/CTP2X7R

Identifiers

PMID37466648
OpenAlexW4384663012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.