Evidence map›Paper›PMID 37466453›Full record

ArticleMicrobiology spectrum2023

Powerful and Real-Time Quantification of Antifungal Efficacy against Triazole-Resistant and -Susceptible Aspergillus fumigatus Infections in Galleria mellonella by Longitudinal Bioluminescence Imaging.

Eliane Vanhoffelen, Lauren Michiels, Matthias Brock, Katrien Lagrou, Agustin Reséndiz-Sharpe, Greetje Vande Velde

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Biomolecular Corona Remodelling ofJournal of extracellular biology · 2026
    Article
  4. Article
  5. Journal of medical microbiology · 2026
    Review
  6. BioluminescentFrontiers in cellular and infection microbiology · 2026
    Article
  7. Drug Discovery and Repurposing forJournal of fungi (Basel, Switzerland) · 2025
    Review
  8. Article
  9. Review
  10. Journal of fungi (Basel, Switzerland) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Pathogens (Basel, Switzerland) · 2024
    Review
  15. Review
  16. AlternativeFrontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eliane VanhoffelenDepartment of Imaging and Pathology, Biomedical MRI Unit/MoSAIC, KU Leuven, Leuven, Belgium.
Lauren MichielsDepartment of Imaging and Pathology, Biomedical MRI Unit/MoSAIC, KU Leuven, Leuven, Belgium.
Matthias BrockSchool of Life Sciences, Fungal Biology Group, University of Nottingham, Nottingham, United Kingdom.ORCID 0000-0003-2774-1856
Katrien LagrouDepartment of Microbiology, Immunology and Transplantation, Laboratory of Clinical Bacteriology and Mycology, KU Leuven, Leuven, Belgium.
Agustin Reséndiz-SharpeDepartment of Imaging and Pathology, Biomedical MRI Unit/MoSAIC, KU Leuven, Leuven, Belgium.
Greetje Vande VeldeDepartment of Imaging and Pathology, Biomedical MRI Unit/MoSAIC, KU Leuven, Leuven, Belgium.ORCID 0000-0002-5633-3993
KU Leuven · BEUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aspergillus fumigatus is an environmental mold that causes life-threatening respiratory infections in immunocompromised patients. The plateaued effectiveness of antifungal therapy and the increasing prevalence of triazole-resistant isolates have led to an urgent need to optimize and expand the current treatment options. For the transition of

Indexed as

Antifungal AgentsMothsAnimalsAspergillus fumigatusDrug Resistance, FungalHumansLarvaMiceMicrobial Sensitivity TestsReproducibility of ResultsTriazolesAntifungal AgentsTriazolesantifungal screeningantifungal therapyaspergillosisAspergillus fumigatusbioluminescence imagingBLIfungal infectionGalleria mellonellatriazole resistance

Identifiers

PMID37466453
PMCPMC10433797
OpenAlexW4384664828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.