ArticleFrontiers in cardiovascular medicine2023
Geriatric nutrition risk index in the prediction of all-cause and cardiovascular mortality in elderly hypertensive population: NHANES 1999-2016.
Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed, 32 citations in OpenAlex.
- Prognostic Value of Inflammatory and Nutritional Indices in Patients Undergoing Permanent Pacemaker Implantation for Degenerative Complete Atrioventricular Block.Medicina (Kaunas, Lithuania) · 2026Article
- Comparing characteristics and outcomes between hospitalized adults on a pea protein or dairy/soy protein formulas: initial findings.Journal of comparative effectiveness research · 2026Article
- Geriatric nutritional risk index and mortality risk in elderly patients with rheumatoid arthritis: evidence from NHANES (1999-2018).Clinical rheumatology · 2026Article
- The Impact of Body Mass Index and Nutritional Status on Cardiac Electrophysiological Balance Using ICEB and ICEBc: A Cross-Sectional Approach.Journal of cardiovascular development and disease · 2026Article
- Article
- The combined effect of geriatric nutritional risk index and abdominal obesity on peripheral arterial disease in an elderly hypertensive population: a longitudinal cohort study.BMC public health · 2025Article
- Joint Associations of the Geriatric Nutrition Risk Index and Frailty with All-Cause and Cause-Specific Mortality in Diabetes Patients: A Prospective Cohort Study.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Declined intrinsic capacity is associated with one-year functional disability in older hypertensive inpatients.BMC geriatrics · 2025Observational
- Association of prognostic nutritional index and severe abdominal aortic calcification in middle-aged adults: a cross-sectional study.BMC cardiovascular disorders · 2025Article
- Review of Blood Pressure Control in Vulnerable Older Adults: The Role of Frailty and Sarcopenia.Journal of vascular diseases · 2025Article
- Predictive values of four nutritional indices for adverse outcomes in patients with hypertension.Clinical and experimental nephrology · 2025Article
- Association between geriatric nutritional risk index and overactive bladder in the elderly population: a cross-sectional study.Frontiers in nutrition · 2025Article
- The relationship between the Geriatric Nutritional Risk Index and all-cause mortality in patients with peripheral artery disease.PloS one · 2025Article
- Predictive Power of Anthropometric Measures and Indices in Assessing Nutrition-Related Risk Using the Geriatric Nutritional Risk Index in Elderly Patients: A Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Association of adipose tissue inflammation and physical fitness in older adults.Immunity & ageing : I & A · 2024Article
- Alcohol drinking triggered decrease of oxidative balance score is associated with high all-cause and cardiovascular mortality in hypertensive individuals: findings from NHANES 1999-2014.Journal of geriatric cardiology : JGC · 2024Article
- Geriatric Nutritional Risk Index is associated with adverse outcomes in patients with hypertension: the Fukushima Cohort study.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- The associations between the Geriatric Nutritional Risk Index and all-cause, cancer-specific, and cardiovascular mortality in the U.S. population: a large-scale pooled survey.Nutrition & metabolism · 2024Article
- Association between geriatric nutritional risk index and depression prevalence in the elderly population in NHANES.BMC public health · 2024Article
- Relationship between Geriatric Nutritional Risk Index with all-cause and CVD mortality in osteopenia and osteoporosis.Frontiers in public health · 2024Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Hypertension is a major risk factor for the global burden of disease, and nutrition is associated with an increased risk of mortality from multiple diseases. Few studies have explored the association of nutritional risk with all-cause mortality and cardiovascular mortality in hypertension, and our study aims to fill this knowledge gap. Method: We included data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2016 on a total of 10,037 elderly patients with hypertension. The nutritional status was evaluated using the Geriatric Nutrition Risk Index (GNRI). Kaplan-Meier survival analysis was performed to analyze the survival rates of different nutritional risk groups. COX proportional risk regression models were used to analyze the predictive effect of GNRI on all-cause mortality and cardiovascular mortality in hypertensive patients. Restricted cubic splines (RCS) were used to explore the nonlinear relationship between GNRI and mortality. Result: The mean age of the hypertensive patients was 70.7 years. A total of 4255 (42.3%) all-cause mortality and 1207 (17.2%) cardiovascular mortality occurred during a median follow-up period of 106 months. Kaplan-Meier showed a more significant reduction in survival for the moderate to severe malnutrition risk of GNRI. The adjusted COX proportional hazards model showed that the hazard ratios for all-cause mortality and cardiovascular mortality in the moderate to severe malnutrition risk group for GNRI were 2.112 (95% CI, 1.377,3.240) and 2.604 (95% CI, 1.603,4.229), respectively. The RCS showed that increased GNRI was associated with a reduced risk of all-cause mortality and cardiovascular mortality risk reduction. Conclusion: Malnutrition exposure assessed by GNRI effectively predicts the risk of all-cause mortality and cardiovascular mortality in the elderly with hypertension.
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