Evidence map›Paper›PMID 37465309›Full record

ArticleACS medicinal chemistry letters2023

Samantha Ottavi, Kelin Li, Jackson G Cacioppo, Andrew J Perkowski, Remya Ramesh, Ben S Gold, Yan Ling, Julia Roberts, Amrita Singh, David Zhang and 7 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Targeting Siderophore Biosynthesis to Thwart Microbial Growth.International journal of molecular sciences · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Samantha OttaviDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0002-2238-7512
Kelin LiDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Jackson G CacioppoDepartment of Chemistry, UNC College of Arts and Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0002-6514-0739
Andrew J PerkowskiDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0009-0000-1143-8962
Remya RameshDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.
Ben S GoldDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.ORCID https://orcid.org/0000-0002-9562-8241
Yan LingDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
Julia RobertsDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
Amrita SinghDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.ORCID https://orcid.org/0000-0001-5649-8483
David ZhangDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
John MosiorDepartments of Biochemistry and Biophysics, Texas Agricultural and Mechanical University, College Station, Texas 77843, United States.
Laurent GoullieuxEvotec ID (Lyon), SAS 40 Avenue Tony Garnier, 69001 Lyon, France.
Christine RoubertEvotec ID (Lyon), SAS 40 Avenue Tony Garnier, 69001 Lyon, France.
Eric BacquéEvotec ID (Lyon), SAS 40 Avenue Tony Garnier, 69001 Lyon, France.
James C SacchettiniDepartments of Biochemistry and Biophysics, Texas Agricultural and Mechanical University, College Station, Texas 77843, United States.ORCID https://orcid.org/0000-0001-5767-2367
Carl F NathanDepartment of Microbiology & Immunology, Weill Cornell Medicine, New York, New York 10065, United States.
Jeffrey AubéDivision of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0003-1049-5767

Funding

Virology Research Program (Program 4)P30CA016086 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI David Darr · 1985 to 2026
$201.5M
Viable but Nonculturable MtbU19AI111143 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI EHRT, SABINE, GLICKMAN, MICHAEL S · 2014 to 2020
$48.6M
Vulnerabilities in Mycobacterial Cell-Wall BiogenesisP01AI095208 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI SACCHETTINI, JAMES C · 2012 to 2022
$19.8M
Phase trafficking in combinatorial chemistry: ROM polymerizationP50GM069663 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI AUBE, JEFFREY · 2003 to 2012
$18.9M
Discovery of Phospopantetheinyl Transferse Inhibitors Against Mycobacterium tuberculosisR01AI155510 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI AUBE, JEFFREY · 2021 to 2024
$3.1M
NCI NIH HHS P30 CA016086NIAID NIH HHS P01 AI095208NIAID NIH HHS R01 AI155510NIAID NIH HHS U19 AI111143NIGMS NIH HHS P50 GM069663
6 · The paper itself

Abstract

4'-Phosphopantetheinyl transferase (PptT) is an essential enzyme for

Identifiers

PMID37465309
PMCPMC10351052

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.