Evidence map›Paper›PMID 37465126›Full record

ArticleFrontiers in endocrinology2023

Mutational profiling of Chinese patients with thyroid cancer.

Yaying Du, Shu Zhang, Gang Zhang, Jiaying Hu, Lianhua Zhao, Yuanyuan Xiong, Lu Shen, Rongrong Chen, Ke Ye, Yan Xu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Can mutation abundance assess the biological behavior of BRAFJournal of translational medicine · 2025
    Article
  5. Article
  6. Thyroid Cancer and Physical Activity: A Bibliometric Analysis.Journal of multidisciplinary healthcare · 2025
    Review
  7. Traditional Chinese Medicine Treatment of Thyroid Cancer: A Review.International journal of general medicine · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yaying DuDepartment of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Shu ZhangDepartment of Breast and Thyroid Surgery, Daping Hospital, Army Military Medical University, Chongqing, China.
Gang ZhangDepartment of Breast and Thyroid Surgery, Daping Hospital, Army Military Medical University, Chongqing, China.
Jiaying HuUltrasound Diagnostic Department, Daping Hospital, Army Military Medical University, Chongqing, China.
Lianhua ZhaoDepartment of Pathology, Daping Hospital, Army Military Medical University, Chongqing, China.
Yuanyuan XiongGeneplus-Beijing, Beijing, China.
Lu ShenGeneplus-Beijing, Beijing, China.
Rongrong ChenGeneplus-Beijing, Beijing, China.
Ke YeDepartment of General Surgery, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yan XuDepartment of Breast and Thyroid Surgery, Daping Hospital, Army Military Medical University, Chongqing, China.
Daping Hospital · CNCentral South University · CNHuazhong University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The incidence of thyroid cancer in China has rapidly increased in recent decades. As the genetic profiles of thyroid cancer vary dramatically between different geographical regions, a comprehensive genetic landscape of thyroid cancer in the Chinese population is urgently needed. Methods: We retrospectively included thyroid cancer patients from three Chinese medical centers between February 2015 and August 2020. To dissect the genomic profiling of these patients, we performed targeted next-generation sequencing on their tumor tissues using a 1,021-gene panel. Results: A total of 458 Chinese patients with thyroid cancer were enrolled, including four malignant histological subtypes arising from follicular epithelial thyroid cells. Conclusion: Our results shed light on the molecular pathogenesis and clinical characteristics of thyroid cancer in the Chinese population. The number of somatic mutations,

Indexed as

Proto-Oncogene Proteins B-rafThyroid NeoplasmsEast Asian PeopleHumansLymphatic MetastasisMutationRetrospective StudiesProto-Oncogene Proteins B-rafclonal architecturegenetic landscapeTERT promoter mutationsthe number of somatic mutationsthyroid cancer

Identifiers

PMID37465126
PMCPMC10351985
OpenAlexW4382939800

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.