Evidence map›Paper›PMID 37464962›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

The MINT Sprint 2.0: A picture naming test for detection of naming impairments in Alzheimer's disease and in preclinical AD.

Tamar H Gollan, Dalia L Garcia, Alena Stasenko, Mayra Murillo, Chi Kim, Douglas Galasko, David P Salmon

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07180147 (Arlington Longitudinal Optimal Healthy Aging Study), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07180147 active not recruitingnot on this mapstarted 2025, after this paper: background citation

Arlington Longitudinal Optimal Healthy Aging Study (ALOHA)

TypeobservationalSponsorMarymount UniversityRan2025 to 2031Enrolled500ConditionsAlzheimer Disease (AD), Cardio Vascular Disease, Mild Cognitive Impairment (MCI), Frailty Syndrome
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Language-dependent expression of anxiety and depression symptoms in Japanese-English bilinguals.Clinical psychological science : a journal of the Association for Psychological Science · 2026
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  7. The MINT Sprint 2.0: a Picture Naming Test for Detection of Naming Impairments in ΜCI Due or Not to AD, Greek Version.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026
    Article
  8. Article
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  10. Syntax drives default language selection in bilingual connected speech production.Journal of experimental psychology. Learning, memory, and cognition · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tamar H GollanDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Dalia L GarciaJoint Doctoral Program in Language and Communicative Disorders, San Diego State University/University of California, San Diego, La Jolla, California, USA.
Alena StasenkoDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Mayra MurilloDepartment of Psychiatry, University of California, San Diego, La Jolla, California, USA.
Chi KimDepartment of Neurosciences, University of California, San Diego and Shiley-Marcos Alzheimer's Disease Research Center, La Jolla, California, USA.
Douglas GalaskoDepartment of Neurosciences, University of California, San Diego and Shiley-Marcos Alzheimer's Disease Research Center, La Jolla, California, USA.
David P SalmonDepartment of Neurosciences, University of California, San Diego and Shiley-Marcos Alzheimer's Disease Research Center, La Jolla, California, USA.
University of California, San Diego · US

Funding

UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GUERRY Marie PEAVY · 2019 to 2026
$34.9M
Language Switching with Alzheimer's DiseaseR01AG076415 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Tamar Gollan · 2022 to 2026
$2.5M
Improving language assessment in bilinguals with epilepsy using advanced neuroimaging and culturally-sensitive neuropsychological measuresF32NS119285 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STASENKO, ALENA · 2021 to 2023
$152k
Speech Markers of Cognition in Aging BilingualismF31AG077915 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GARCIA, DALIA · 2022 to 2024
$125k
NIA NIH HHS F31 AG077915NIA NIH HHS P30 AG062429NIA NIH HHS R01 AG076415NIH HHS AG076415NIH HHS AG077915NIH HHS NS119285NIH HHS P30-AG062429NINDS NIH HHS F32 NS119285
6 · The paper itself

Abstract

introductionEvidence on the onset of naming deficits in Alzheimer's disease (AD) is mixed. Some studies showed an early decline, but others did not. The present study introduces evidence from a novel naming test.

methodsCognitively normal (n = 138), mild cognitive impairment (MCI; n = 21), and Alzheimer's disease (AD; n = 31) groups completed an expanded Multilingual Naming Test with a time-pressured administration procedure (MINT Sprint 2.0). Cerebrospinal fluid biomarkers classified participants as true controls (n = 61) or preclinical AD (n = 26).

resultsTotal correct MINT Sprint 2.0 scores exhibited good sensitivity and specificity (>0.85) for discriminating true controls from cognitively impaired (MCI/AD) groups and showed significant differences between true controls and preclinical AD groups. Time measurement did not improve classification, but percent resolved scores exhibited promise as an independent AD marker. DISCUSSION: Naming deficits can be detected in the earliest stages of AD with tests and procedures designed for this purpose.

Indexed as

Alzheimer DiseaseCognitive DysfunctionMultilingualismBiomarkersHumansNeuropsychological TestsSensitivity and SpecificityBiomarkersagingcerebrospinal fluid biomarkersmultilingual naming test (MINT)picture namingpreclinical Alzheimer's diseasespeeded naming

Identifiers

PMID37464962
PMCPMC10916946
OpenAlexW4384664563

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.