ReviewCurrent treatment options in oncology2023
Gastric Cancer with Sarcopenia: an Area Worth Focusing On.
Review in Current treatment options in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and prognostic value of sarcopenia in patients with bladder cancer undergoing radical cystectomy: a systematic review and meta-analysis.Frontiers in oncology · 2025Pooled it
- The association between gastric cancer and sarcopenia: a scoping review.Frontiers in oncology · 2025Pooled it
- The Value of the Albumin-Myosteatosis Gauge in Predicting the Postoperative Outcomes of Non-Metastatic Gastric Cancer.Cancers · 2026Article
- Pretreatment C-reactive protein-triglyceride-glucose index predicts survival in patients with FLOT-treated locally advanced gastric and gastroesophageal junction cancer.Oncology letters · 2026Article
- RBPMS2 can inhibit the NLRP3 / caspase-1 / GSDMD signaling pathway to resist pyroptosis in gastric cancer cells.Scientific reports · 2025Article
- Predictive value of preoperative L3-SMI, AGR, and PNI for overall survival in patients undergoing radical gastrectomy for gastric cancer.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- Effectiveness of home-based exercise combined with nutritional care intervention in elderly patients with gastric cancer and sarcopenia: a retrospective study.Frontiers in medicine · 2025Article
- Identification of postoperative weight loss trajectories and development of a machine learning-based tool for predicting malnutrition in gastric cancer patients.Frontiers in nutrition · 2025Article
- The alkaline phosphatase-to-prealbumin ratio combined with CT-quantified sarcopenia predicts survival in gastric cancer patients after surgical resection.Frontiers in nutrition · 2025Article
- Geriatric Nutrition Risk Index is closely associated with sarcopenia and quality of life in gastric cancer patients: a cross-sectional study.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
opinion statementGastric cancer (GC) is the fifth most common cancer and the third leading cause of cancer death worldwide, which seriously endangers human health. A number of studies have shown that sarcopenia occurs more frequently in patients with gastric cancer than in the general population and can significantly affect the disease status and survival of patients, which is of great significance in predicting the prognosis of gastric cancer. Patients with gastric cancer may suffer sarcopenia no matter before or after surgery, and the pathogenesis is complex. Abnormal nutrient metabolism and reduced exercise are the leading causes. In addition, surgical treatment and chemotherapy for gastric cancer might participate in the physiological and pathological mechanism of sarcopenia. Generally speaking, exercise and nutritional therapy are the main prevention and treatment methods for sarcopenia. But more prospective evidence is needed to establish reasonable interventions, and other drug treatments are in their infancy. For the diagnostic criteria of sarcopenia, the cut-off values of the skeletal muscle mass index obtained from CT images vary widely and need to be standardized and unified. We also need to explore simple predictors to facilitate sarcopenia risk assessment. More research is needed to formulate more appropriate treatments for gastric cancer patients with sarcopenia.
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