ArticlePediatric surgery international2023
Gastrointestinal quality of life and bowel function in adults born with anorectal malformation and hirschsprung disease.
Article in Pediatric surgery international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Life outcomes of being born with anorectal malformation: a systematic review of intersectional reporting, mental health co-morbidities, and psychosocial experiences in adulthood.Pediatric surgery international · 2026Pooled it
- Permanent enterostomy in Hirschsprung disease: can we predict which patients are at risk?Pediatric surgery international · 2026Article
- Laparoscopic Versus Robotic Yancey-Soave Primary Pull-Through in Rectosigmoid Hirschsprung Disease: A Systematic Review of the Literature.Children (Basel, Switzerland) · 2026Review
- Familial, environmental, and pregnancy-related risk factors for anorectal malformations in Pakistani newborns: a hospital-based case-control study.BMC pediatrics · 2026Article
- Long-Term Bowel and Urinary Function Outcomes and Quality of Life in Patients with Anorectal Malformations: 20 Years of Experience.Children (Basel, Switzerland) · 2025Article
- Review
- Gender differences in self-reported quality of life and bowel function among patients with anorectal malformation and Hirschsprung's disease compared to a healthy population: a multicenter cross-sectional study.Pediatric surgery international · 2025Article
- Integrating psychological support in the care of children and adolescents with anorectal malformation or Hirschsprung disease: a ten-year experience.Pediatric surgery international · 2025Observational
- Bowel Function Score in Long-Term Follow-Up for Children with Hirschsprung Disease: OASIS-Holistic Care in Hirschsprung Disease Network Position Paper.Children (Basel, Switzerland) · 2024Article
- Correlation between congenital pelvic floor muscle development assessed by magnetic resonance imaging and postoperative defecation.Pediatric surgery international · 2024Article
- Long-term outcomes and quality of life in patients with Hirschsprung disease.World journal of pediatric surgery · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo assess the quality of life and disease-specific functioning of adults with anorectal malformations (ARM) or Hirschsprung disease (HD) compared to healthy reference scores.
methodsPatients with the diagnosis of ARM or HD from the Adult Colorectal Research Registry completed the Short Form 36 Health Survey (SF-36), the Gastrointestinal Quality of Life Index (GIQoLI), and the Bowel Function Score (BFS) between October 2019 and August 2022. One-sample Wilcoxon test compared the results to reported healthy references with a significance level of < 0.05.
resultsThe response rate was 67%. All three surveys were completed by 133 adults with a slight preponderance of males (51%). Median age was 31 years, 117 were born with ARM and 16 with HD. All subgroups had significantly lower BFS than healthy references. ARM patients scored significantly lower than the healthy reference population when assessed for GIQoL. All showed significant impairment with the mental component summary (MCS) of SF-36. Patients with a successful bowel management had significantly higher scores on all three questionnaires than those with fecal accidents.
conclusionOur results emphasize the importance of a successful bowel management and its impact on the quality of life and bowel function. Long-term follow-up is recommended with attention to mental health.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.