ArticleClinical oral investigations2023
Evaluation of 3D MRI for early detection of bone edema associated with apical periodontitis.
Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.
- Comparative Analysis of 3D Imaging in Periodontal Disease Assessment: A Systematic Review and Meta-Analysis.Clinical and experimental dental research · 2025Pooled it
- A Pilot Comparative Study of Multi-Contrast Dental MRI and CBCT: Clinical Correlates of Disease Status and Inflammatory Burden in Periodontitis.Journal of clinical periodontology · 2026Article
- Caries imaging using T1 StarVIBE and PETRA sequences compared to normal dental work-up: a proof-of-concept study.Oral radiology · 2026Article
- Impact of sequence selection on postoperative MRI interpretability and artifact reduction in simulated mandibular trauma.Frontiers in oral health · 2026Article
- Evaluation of inflammatory vascular responses in patients with severe periodontitis by contrast-enhanced perfusion dental MRI.European radiology experimental · 2025Article
- Dental magnetic resonance imaging for bone loss assessment and disease activity classification in severe periodontitis.Insights into imaging · 2025Article
- Periapical bone edema volume in 3D MRI is positively correlated with bone architecture changes.Insights into imaging · 2025Article
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo detect and evaluate early signs of apical periodontitis using MRI based on a 3D short-tau-inversion-recovery (STIR) sequence compared to conventional panoramic radiography (OPT) and periapical radiographs in patients with apical periodontitis. MATERIALS AND
methodsPatients with clinical evidence of periodontal disease were enrolled prospectively and received OPT as well as MRI of the viscerocranium including a 3D-STIR sequence. The MRI sequences were assessed for the occurrence and extent of bone changes associated with apical periodontitis including bone edema, periradicular cysts, and dental granulomas. OPTs and intraoral periapical radiographs, if available, were assessed for corresponding periapical radiolucencies using the periapical index (PAI).
resultsIn total, 232 teeth of 37 patients (mean age 62±13.9 years, 18 women) were assessed. In 69 cases reactive bone edema was detected on MRI with corresponding radiolucency according to OPT. In 105 cases edema was detected without corresponding radiolucency on OPT. The overall extent of edema measured on MRI was significantly larger compared to the radiolucency on OPT (mean: STIR 2.4±1.4 mm, dental radiograph 1.3±1.2 mm, OPT 0.8±1.1 mm, P=0.01). The overall PAI score was significantly higher on MRI compared to OPT (mean PAI: STIR 1.9±0.7, dental radiograph 1.3±0.5, OPT 1.2±0.7, P=0.02).
conclusionEarly detection and assessment of bone changes of apical periodontitis using MRI was feasible while the extent of bone edema measured on MRI exceeded the radiolucencies measured on OPT. CLINICAL RELEVANCE: In clinical routine, dental MRI might be useful for early detection and assessment of apical periodontitis before irreversible bone loss is detected on conventional panoramic and intraoral periapical radiographs.
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