Evidence map›Paper›PMID 37464070›Full record

ArticleLeukemia2023

Pharmacological inhibition of METTL3 impacts specific haematopoietic lineages.

Katherine Sturgess, Eliza Yankova, M S Vijayabaskar, Tomoya Isobe, Justyna Rak, Iwo Kucinski, Melania Barile, Natalie A Webster, Maria Eleftheriou, Rebecca Hannah and 6 more

Abstract read
In one paragraph

Article in Leukemia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
  3. Targeting mDiscover oncology · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. RNA modification systems as therapeutic targets.Nature reviews. Drug discovery · 2026
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Katherine SturgessWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Eliza YankovaWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
M S VijayabaskarWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Tomoya IsobeWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID 0000-0002-3487-3307
Justyna RakWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Iwo KucinskiWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID 0000-0002-9385-0359
Melania BarileWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Natalie A WebsterStorm Therapeutics Ltd, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Maria EleftheriouWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Rebecca HannahWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
Malgorzata GozdeckaWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.
George VassiliouWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID 0000-0003-4337-8022
Oliver RauschStorm Therapeutics Ltd, Babraham Research Campus, Cambridge, CB22 3AT, UK.
Nicola K WilsonWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK.ORCID 0000-0003-0865-7333
Berthold GöttgensWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK. bg200@cam.ac.uk.ORCID 0000-0001-6302-5705
Konstantinos TzelepisWellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, CB2 0AW, UK. kt404@cam.ac.uk.ORCID 0000-0002-4865-7648

Funding

Cancer Research UK 21762Cancer Research UK 23015Medical Research CouncilWellcome Trust 206328/Z/17/ZWellcome Trust 210926/Z/18/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Hematopoietic SystemMethyltransferasesHumansMethyltransferasesMETTL3 protein, human

Identifiers

PMID37464070
PMCPMC10539174

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.