ReviewNature medicine2023
Adverse childhood experiences and lifelong health.
Review in Nature medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
83 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Psychological factors mediating/moderating the association between adverse childhood experiences and suicidal ideation in young people: a systematic review.European child & adolescent psychiatry · 2026Pooled it
- Association between adverse childhood experiences and asthma: a meta-analysis.BMC public health · 2026Pooled it
- Increasing familial engagement in family violence services: a systematically conducted realist review of barriers and facilitators.Frontiers in psychiatry · 2026Pooled it
- Impact of Early Postnatal Maternal Separation Stress on Pancreatic Function in Rodents: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- Adverse childhood experiences contribute to blood pressure changes in adulthood: a meta-analysis of over 750 000 adults.Journal of global health · 2025Pooled it
- Health effects associated with exposure of children to physical violence, psychological violence and neglect: a Burden of Proof study.Nature human behaviour · 2025Pooled it
- Risk and protective factors of depression among caregivers of children with disabilities in rural Rwanda.BMJ global health · 2026Trial
- Longitudinal associations between patterns of childhood adverse experiences and positive experiences and depression and anxiety symptom trajectories among college students.European journal of psychotraumatology · 2026Article
- Adolescents' and parents' perspectives on addressing adverse childhood experiences in school-based health centers.Pediatric research · 2026Article
- Article
- Feasibility of an Online Resilience Program for Mothers With Adverse Childhood Experiences.Research in nursing & health · 2026Article
- Frequency and Association between Adverse Childhood Experiences and Psychiatric Outcomes Among Treatment-seeking Patients with Severe Obesity: a Retrospective Observational Study.Obesity surgery · 2026Observational
- Adverse Childhood Experiences and HIV Prevalence Among Adolescent Girls and Young Women in Rural South Africa: The Role of Household and Community Violence.AIDS and behavior · 2026Article
- Article
- Trauma Symptoms, Life Satisfaction, and Perceived Happiness as Predictors of Mental Health in Displaced Children and Adolescents in Niger.Journal of child & adolescent trauma · 2026Article
- Association of traumatic experiences with depressive symptoms among LGBTQ+ population in China.Nature human behaviour · 2026Article
- Positive affect as a developmental mediator of early adversity and internalizing psychopathology.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Psychometric properties and network analysis of the brief Adverse Childhood Experiences Abuse Short Form (ACE-ASF) in homosexual and heterosexual.BMC psychology · 2026Article
- Emerging Perspectives on Adverse Childhood Experiences and Brain Cancer Immunotherapy.Cancers · 2026Article
- Effectiveness of a training programme on frontline workers' skills and competencies in promoting safe and stable nurturing relationships: A quasi-experimental study from rural central India.The Indian journal of medical research · 2026Article
23 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
With the advent of the sustainable development goals, the field of global child health has shifted its focus from reducing mortality to improving health, nutrition and development outcomes - often measured as human capital. A growing knowledge of the biology of development and neuroscience has highlighted the importance of adverse environmental exposures, collectively termed adverse childhood experiences (ACEs) on health outcomes. ACEs are associated with short-term, medium-term and long-term negative consequences for health and development and their effects may be multiplicative, especially during critical periods of sensitivity and developmental plasticity. Some of these effects are compounded by emerging global threats such as climate change, conflict and population displacement. In this Review, we discuss the key mechanisms linking ACEs to health outcomes and consider promising strategies to prevent and mitigate their effects, highlighting evidence from programs in low-income and middle-income countries. Finally, we emphasize the need for early recognition of ACEs and delivery of packages of interventions spanning key sectors such as health, education, women's empowerment and social protection.
Indexed as
Identifiers
37464047What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.