Evidence map›Paper›PMID 37464013›Full record

ArticleCommunications biology2023

Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter.

Julian Alexander Schreiber, Anastasia Derksen, Gunnar Goerges, Sven Schütte, Jasmin Sörgel, Aytug K Kiper, Nathalie Strutz-Seebohm, Tobias Ruck, Sven G Meuth, Niels Decher and 1 more

Abstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Structure-Function Relationships of KAdvances in experimental medicine and biology · 2026
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Julian Alexander SchreiberInstitute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany. j.schreiber@uni-muenster.de.ORCID 0000-0002-3847-7539
Anastasia DerksenWestfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.
Gunnar GoergesInstitute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.
Sven SchütteInstitute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
Jasmin SörgelWestfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.
Aytug K KiperInstitute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.ORCID 0000-0003-2850-2523
Nathalie Strutz-SeebohmInstitute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.
Tobias RuckDepartment of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.ORCID 0000-0001-6332-8650
Sven G MeuthDepartment of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Niels DecherInstitute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.ORCID 0000-0002-9433-687X
Guiscard SeebohmInstitute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.ORCID 0000-0001-9303-5373

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The TWIK-related spinal cord K

Indexed as

ChloroquinolinolsPotassium ChannelsBinding SitesMembrane PotentialsChloroquinolinolscloxyquinPotassium Channels

Identifiers

PMID37464013
PMCPMC10354012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.