Evidence map›Paper›PMID 37463839›Full record

Trial reportEthnicity & health2024

Cognitive prescriptions for reducing dementia risk factors among Black/African Americans: feasibility, acceptability, and preliminary efficacy.

Pariya L Fazeli, Cierra Hopkins, David E Vance, Virginia Wadley, Peng Li, Bulent Turan, Danny H Wang, Pamela G Bowen, Olivio J Clay

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Ethnicity & health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03864536 (A Multidomain Approach to Preventing Dementia in African Americans), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03864536 nacompletednot on this map

A Multidomain Approach to Preventing Dementia in African Americans: Cognitive Prescriptions

TypeinterventionalSponsorUniversity of Alabama at BirminghamRan2020 to 2022Enrolled39ConditionsCognitive Change, Health Behavior, Health LiteracyArmsCognitive Prescriptions
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Cierra HopkinsSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Virginia WadleySchool of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Peng LiSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Bulent TuranDepartment of Psychology, Koc University, Istanbul, Turkey.
Danny H WangDepartment of Biobehavioral Health, College of Health and Human Development, The Pennsylvania State University, State College, PA, USA.
Pamela G BowenSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Olivio J ClayDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USKoç University · TRPennsylvania State University · US

Funding

Evaluation of Neurobiological Mechanisms Mediating the Effect of Immune Activation on Neurocognitive Impairment and the Role of Psychosocial Factors Among Women Living with HIVR01MH131177 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Andrea Norcini Pala, Pariya Fazeli Wheeler · 2022 to 2026
$3.3M
UAB Alzheimer's Disease Research CenterP20AG068024 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GELDMACHER, DAVID S · 2020 to 2022
$3.3M
An RCT of Speed of Processing Training in Middle-Aged and Older Adults with HIVR01MH106366 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2016 to 2020
$2.6M
Testing the Efficacy and Mechanisms of an Adapted Resilience Building Intervention in People Aging with HIVR21AG076377 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WHEELER, PARIYA FAZELI · 2022 to 2023
$520k
A Multidomain Approach to Preventing Dementia in African Americans: Cognitive PrescriptionsR21AG059954 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WHEELER, PARIYA FAZELI · 2019 to 2020
$408k
Executive Function Training to Reduce Cognitive Intra-Individual Variability in Adults with HIVR21AG077957 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2022 to 2023
$408k
NIA NIH HHS P20 AG068024NIA NIH HHS R21 AG059954NIA NIH HHS R21 AG076377NIA NIH HHS R21 AG077957NIMH NIH HHS R01 MH106366NIMH NIH HHS R01 MH131177
6 · The paper itself

Abstract

objectivesBlack/African Americans (B/AAs) have double the risk of Alzheimer's disease and related dementia than Whites, which is largely driven by health behaviors. This study examined the feasibility, acceptability, and preliminary efficacy of a pilot randomized clinical trial of an individualized multidomain health behavior intervention among middle-aged and older B/AAs (dubbed Cognitive Prescriptions [CogRx]).

designThirty-nine community-dwelling B/AA participants aged 45-65 without significant cognitive impairment were randomized to one of three groups: CogRx, Psychoeducation, or no-contact control. The Psychoeducation and CogRx groups received material on dementia prevalence, prognosis, and risk factors, while the CogRx group additionally received information on their risk factor profile across the five CogRx domains (physical, cognitive, and social activity, diet, sleep). This information was used for developing tailored 3-month goals in their suboptimal areas.

resultsThe CogRx program had high retention (all 13 CogRx participants completed the 3-month program and 97% of the full sample completed at least 1 follow-up) and was well-received as exhibited by qualitative and quantitative feedback. Themes identified in the positive feedback provided by participants on the program included: increased knowledge, goal-setting, personalization, and motivation. The COVID-19 pandemic was a consistent theme that emerged regarding barriers of adherence to the program. All three groups improved on dementia knowledge, with the largest effects observed in CogRx and Psychoeducation groups. Increases in cognitive, physical, and overall leisure activities favored the CogRx group, whereas improvements in sleep outcomes favored Psychoeducation and CogRx groups as compared to the control group.

conclusionThe CogRx program demonstrated feasibility, acceptability, and preliminary efficacy in increasing dementia knowledge and targeted health behaviors. Further refinement and testing of the implementation and effectiveness of similar person-centered dementia prevention approaches are needed on a larger scale in diverse populations. Such findings may have implications for clinical and public health recommendations.

trial registrationClinicalTrials.gov identifier: NCT03864536.

Indexed as

Alzheimer DiseaseBlack or African AmericanDementiaAgedCognitionFeasibility StudiesHealth BehaviorHumansMiddle AgedPandemicsRisk FactorsAlzheimer’s diseasebehavior changeLeisure activitiesracial disparities

Identifiers

PMID37463839
PMCPMC11232533
OpenAlexW4384644227

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.