ArticleRespiratory care2023
Airway and Transpulmonary Driving Pressure by End-Inspiratory Holds During Pressure Support Ventilation.
Article in Respiratory care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Monitoring of breathing effort through pressure time product measurement using airway occlusion pressure (PTPBMC anesthesiology · 2026Trial
- Personalized positive end-expiratory pressure in spontaneously breathing patients with acute respiratory distress syndrome by simultaneous electrical impedance tomography and transpulmonary pressure monitoring: a randomized crossover trial.Intensive care medicine · 2024Trial
- The impact of a lung-protective ventilation mode using transpulmonary driving pressure titrated positive end-expiratory pressure on the prognosis of patients with acute respiratory distress syndrome.Journal of clinical monitoring and computing · 2024Trial
- Individualized Perioperative PEEP in Older Surgical Patients: A Three-Dimensional Titration Framework.Clinical interventions in aging · 2026Review
- Article
- Driving pressure of respiratory system and lung stress in mechanically ventilated patients with active breathing.Critical care (London, England) · 2024Observational
- Airway Versus Transpulmonary Driving Pressures During Pressure Support Ventilation in ARDS.Respiratory care · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe precision of quasi-static airway driving pressure (ΔP) assessed in pressure support ventilation (PSV) as a surrogate of tidal lung stress is debatable because persistent muscular activity frequently alters the readability of end-inspiratory holds. In this study, we used strict criteria to discard excessive muscular activity during holds and assessed the accuracy of ΔP in predicting global lung stress in PSV. Additionally, we explored whether the physiological effects of high PEEP differed according to the response of respiratory system compliance (C
methodsAdults with ARDS undergoing PSV were enrolled. An esophageal catheter was inserted to calculate lung stress through transpulmonary driving pressure (ΔP
resultsEighteen subjects and 162 end-inspiratory holds were analyzed; 51/162 (31.5%) of the holds had ΔP
conclusionsIn subjects with ARDS undergoing PSV, high ΔP assessed by readable end-inspiratory holds accurately detected potentially dangerous thresholds of ΔP
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Registered trials
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