Evidence map›Paper›PMID 37463675›Full record

ArticleAdvanced healthcare materials2023

X-Ray Nanothermometry of Nanoparticles in Tumor-Mimicking Tissues under Photothermia.

Rosalía López-Méndez, Javier Reguera, Alexandre Fromain, Esraa Samy Abu Serea, Eva Céspedes, Francisco Jose Teran, Fangyuan Zheng, Ana Parente, Miguel Ángel García, Emiliano Fonda and 4 more

Erratum issuedAbstract read
In one paragraph

Article in Advanced healthcare materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. CuACS applied nano materials · 2024
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Rosalía López-MéndezIMDEA Nanociencia, c/ Faraday, 9, Madrid, 28049, Spain.
Javier RegueraBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940, Leioa, Spain.
Alexandre FromainLaboratoire Physico Chimie Curie, PCC, CNRS UMR168, Institut Curie, Sorbonne University, PSL University, Paris, 75005, France.
Esraa Samy Abu SereaBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940, Leioa, Spain.
Eva CéspedesInstituto de Ciencia de Materiales de Madrid, ICMM-CSIC, Madrid, 28049, Spain.
Francisco Jose TeranIMDEA Nanociencia, c/ Faraday, 9, Madrid, 28049, Spain.
Fangyuan ZhengBCMaterials, Basque Center for Materials, Applications and Nanostructures, UPV/EHU Science Park, 48940, Leioa, Spain.
Ana ParenteDpto. Física Materiales, Facultad CC. Físicas, Universidad Complutense de Madrid, Madrid, 28040, Spain.
Miguel Ángel GarcíaDepartamento de Electrocerámica, Instituto de Cerámica y Vidrio, ICV-CSIC, Kelsen 5, Madrid, 28049, Spain.
Emiliano FondaSynchrotron SOLEIL, L'Orme des Merisiers - St. Aubin-BP 48, Gif s/ Yvette, 91192, France.
Julio CamareroIMDEA Nanociencia, c/ Faraday, 9, Madrid, 28049, Spain.
Claire WilhelmLaboratoire Physico Chimie Curie, PCC, CNRS UMR168, Institut Curie, Sorbonne University, PSL University, Paris, 75005, France.ORCID 0000-0001-7024-9627
Álvaro Muñoz-NovalDpto. Física Materiales, Facultad CC. Físicas, Universidad Complutense de Madrid, Madrid, 28040, Spain.
Ana EspinosaIMDEA Nanociencia, c/ Faraday, 9, Madrid, 28049, Spain.ORCID 0000-0002-5626-6129

Funding

Comunidad de Madrid 2018-T1/IND-1005(A.E.)Comunidad de Madrid 2018-T1/IND-10360 projectComunidad de Madrid 2022-5A/IND-24234 project (A. M-N.)Comunidad de Madrid ASAP-CMS2022/BMD-7434project(A.E.)Comunidad de Madrid NanoMagCOSTCMS2018/NMT-4321projectConsejo Superior de Investigaciones Científicas PIE-20226AT024Ministerio de Ciencia e Innovación CEX2020-001039-SMinisterio de Ciencia e Innovación PID2019-106099RB-C43/AEI/10.13039/501100011033(J.R.)Ministerio de Ciencia e Innovación PID2021-126323OA-I00(A.M-N)Ministerio de Ciencia e Innovación PID2021-127033OB-C21(A.E.)Ministerio de Ciencia e Innovación PRE2020-96246grant(R.L-M.)Ministerio de Ciencia e Innovación RYC2020-029282-I(A.E.)Ministerio de Ciencia e Innovación SEV-2016-0686"Severo Ochoa" program for Centres of Excellence in R&D CEX2020-001039-S"Severo Ochoa" program for Centres of Excellence in R&D SEV-2016-0686
6 · The paper itself

Abstract

Temperature plays a critical role in regulating body mechanisms and indicating inflammatory processes. Local temperature increments above 42 °C are shown to kill cancer cells in tumorous tissue, leading to the development of nanoparticle-mediated thermo-therapeutic strategies for fighting oncological diseases. Remarkably, these therapeutic effects can occur without macroscopic temperature rise, suggesting localized nanoparticle heating, and minimizing side effects on healthy tissues. Nanothermometry has received considerable attention as a means of developing nanothermosensing approaches to monitor the temperature at the core of nanoparticle atoms inside cells. In this study, a label-free, direct, and universal nanoscale thermometry is proposed to monitor the thermal processes of nanoparticles under photoexcitation in the tumor environment. Gold-iron oxide nanohybrids are utilized as multifunctional photothermal agents internalized in a 3D tumor model of glioblastoma that mimics the in vivo scenario. The local temperature under near-infrared photo-excitation is monitored by X-ray absorption spectroscopy (XAS) at the Au L

Indexed as

NanoparticlesNeoplasmsThermometryGoldHumansTemperatureX-RaysGoldnanomedicinesnanothermal therapynanothermometryphotothermiaplasmonic nanoparticlesX-ray absorption spectroscopy

Identifiers

PMID37463675
PMCPMC11469036

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.