Evidence map›Paper›PMID 37462831›Full record

ArticleTranslational stroke research2024

TRPC Channels Activated by G Protein-Coupled Receptors Drive Ca

Jasneet Parmar, Georg von Jonquieres, Nagarajesh Gorlamandala, Brandon Chung, Amanda J Craig, Jeremy L Pinyon, Lutz Birnbaumer, Matthias Klugmann, Andrew J Moorhouse, John M Power and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Translational stroke research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jasneet ParmarTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0002-0285-8698
Georg von JonquieresTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0002-7423-3355
Nagarajesh GorlamandalaTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0003-4385-5271
Brandon ChungTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Amanda J CraigTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0002-7197-4369
Jeremy L PinyonTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.
Lutz BirnbaumerInstitute of Biomedical Research (BIOMED), Pontifical Catholic University of Argentina, Av. A Moreau de Justo 1300, C1107AFF, Buenos Aires CABA, Argentina.ORCID 0000-0002-0775-8661
Matthias KlugmannTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0003-0574-612X
Andrew J MoorhouseTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0001-7957-2498
John M PowerTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia.ORCID 0000-0002-2478-8416
Gary D HousleyTranslational Neuroscience Facility and Department of Physiology, School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, 2052, Australia. g.housley@unsw.edu.au.ORCID 0000-0002-8413-588X

Funding

Transmembrane Signaling Mechanisms Involving TRP ChannelsZ01ES101684 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI BIRNBAUMER, LUTZ · 2003 to 2008
$2.1M
Intramural NIH HHS Z01 ES101684
6 · The paper itself

Abstract

Canonical transient receptor potential (TRPC) non-selective cation channels, particularly those assembled with TRPC3, TRPC6, and TRPC7 subunits, are coupled to G

Indexed as

Disease Models, AnimalMice, KnockoutReceptors, G-Protein-CoupledTRPC Cation ChannelsAnimalsBrain InjuriesCalciumMaleMiceMice, Inbred C57BLPurkinje CellsCalciumReceptors, G-Protein-CoupledTRPC Cation ChannelsAAVrh20-GCaMP5g genetically encoded Ca2+ reporterGAD67-GFP-Trpc3 KO)Glutamate excitotoxicityNeuroprotectionPhotothrombotic focal ischemic brain injury modelTrpc1/3/6/7Trpc knockout mouse models (Trpc3

Identifiers

PMID37462831
PMCPMC11226524

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.