Evidence map›Paper›PMID 37462812›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2024

Frequency and predictors of concurrent complications in multi-suture release for syndromic craniosynostosis.

Sujay Rajkumar, Daniel S Ikeda, Michaela Scanlon, Margaret Shields, John R Kestle, Jillian Plonsker, Michael Brandel, David D Gonda, Michael Levy, Donald J Lucas and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 9 citations in OpenAlex.

  1. Experiences of surgical complications and reoperations in nonsyndromic sagittal synostosis patients in Oulu.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Sujay RajkumarDrexel University School of Medicine, Philadelphia, PA, USA.
Daniel S IkedaDepartment of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, MD, USA.ORCID 0000-0002-7615-4589
Michaela ScanlonDepartment of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Margaret ShieldsDepartment of Neurosurgery, Walter Reed National Military Medical Center, Bethesda, MD, USA.
John R KestleDivision of Pediatric Neurosurgery, Primary Children's Hospital, Salt Lake City, UT, USA.
Jillian PlonskerDepartment of Neurosurgery, University of California San Diego, San Diego, CA, USA.
Michael BrandelDepartment of Neurosurgery, University of California San Diego, San Diego, CA, USA.
David D GondaDepartment of Neurosurgery, University of California San Diego, San Diego, CA, USA.
Michael LevyDepartment of Neurosurgery, University of California San Diego, San Diego, CA, USA.
Donald J LucasDivision of Pediatric Surgery, Department of General Surgery, Naval Medical Center San Diego, San Diego, CA, USA.
Pamela M ChoiDivision of Pediatric Surgery, Department of General Surgery, Naval Medical Center San Diego, San Diego, CA, USA.
Vijay M RavindraDepartment of Neurosurgery, Naval Medical Center San Diego, San Diego, CA, USA. vijay.ravindra@hsc.utah.edu.ORCID 0000-0002-4496-7622
Naval Medical Center San Diego · USUniversity of California San Diego · USDrexel University · USPrimary Children's Hospital · USWalter Reed National Military Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUnderstanding the complication profile of craniosynostosis surgery is important, yet little is known about complication co-occurrence in syndromic children after multi-suture craniosynostosis surgery. We examined concurrent perioperative complications and predictive factors in this population.

methodsIn this retrospective cohort study, children with syndromic diagnoses and multi-suture involvement who underwent craniosynostosis surgery in 2012-2020 were identified from the National Surgical Quality Improvement Program-Pediatric database. The primary outcome was concurrent complications; factors associated with concurrent complications were identified. Correlations between complications and patient outcomes were assessed.

resultsAmong 5,848 children identified, 161 children (2.75%) had concurrent complications: 129 (2.21%) experienced two complications and 32 (0.55%) experienced ≥ 3. The most frequent complication was bleeding/transfusion (69.53%). The most common concurrent complications were transfusion/superficial infection (27.95%) and transfusion/deep incisional infection (13.04%) or transfusion/sepsis (13.04%). Two cardiac factors (major cardiac risk factors (odds ratio (OR) 3.50 [1.92-6.38]) and previous cardiac surgery (OR 4.87 [2.36-10.04])), two pulmonary factors (preoperative ventilator dependence (OR 3.27 [1.16-9.21]) and structural pulmonary/airway abnormalities (OR 2.89 [2.05-4.08])), and preoperative nutritional support (OR 4.05 [2.34-7.01]) were independently associated with concurrent complications. Children who received blood transfusion had higher odds of deep surgical site infection (OR 4.62 [1.08-19.73]; p = 0.04).

conclusionsOur results indicate that several cardiac and pulmonary risk factors, along with preoperative nutritional support, were independently associated with concurrent complications but procedural factors were not. This information can help inform presurgical counseling and preoperative risk stratification in this population.

Indexed as

CraniosynostosesNeurosurgical ProceduresChildHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsSurgical Wound InfectionSuturesComplicationConcurrentCraniosynostosisNational Surgical Quality Improvement ProgramPediatricPerioperative

Identifiers

PMID37462812
PMCPMC10761552
OpenAlexW4384626695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.