Evidence map›Paper›PMID 37462776›Full record

ArticleCurrent microbiology2023

Docking Studies on Biomolecules from Marine Microalga Skeletonema costatum Against Hemolysin Protein of Bioluminescence Disease-Causing Vibrio harveyi.

Krishnamoorthy Sivakumar, Sudalayandi Kannappan, Balakrishnan Vijayakumar

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Current microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Krishnamoorthy SivakumarICAR - Krishi Vigyan Kendra, Tamil Nadu Veterinary and Animal Sciences University (TANUVAS), Kattupakkam, Chennai, Tamil Nadu, 603 203, India. ksivafbt@gmail.com.ORCID http://orcid.org/0000-0003-3385-6158
Sudalayandi KannappanCrustacean Culture Division, ICAR - Central Institute of Brackishwater Aquaculture (CIBA), Chennai, Tamil Nadu, 600 028, India.ORCID http://orcid.org/0000-0001-9825-7813
Balakrishnan VijayakumarCentre of Advance Study in Crystallography and Biophysics, University of Madras, Chennai, Tamil Nadu, 600 025, India.ORCID http://orcid.org/0000-0002-3570-4732
Central Institute of Brackishwater Aquaculture · INTamil Nadu Veterinary and Animal Sciences University · INUniversity of Wisconsin–Madison · US

Funding

Department of Biotechnology, Ministry of Science and Technology, India BT/PR/13383/AAQ/03/501/2009
6 · The paper itself

Abstract

Grow-out and hatchery units of shrimps are being impacted by disease-causing bacterial pathogens and predominantly marine Vibrios. The use of chemicals for governing bacterial pathogens in the aquaculture practices is developing resistance to bacteria. Henceforth, the application of bio-therapeutic agents from marine resources for controlling pathogens is most vital to be considered. Molecular docking is computer-assisted drug design tool to detect and counteract for drug-receptor interaction for known target protein of diseases. Therefore, an effort was made with the extract of the marine micro alga Skeletonema costatum against hemolysin protein of pathogenic bacteria Vibrio harveyi. The extract of S. costatum was tested against growth and virulence produced by V. harveyi during larviculture of Penaeus monodon. The extract was analyzed for phyto-constituents through GC-MS and used them as ligand molecule in docking. S. costatum extract at 200 µg mL

Indexed as

MicroalgaeVibrioHemolysin ProteinsMolecular Docking SimulationHemolysin Proteins

Identifiers

PMID37462776
OpenAlexW4384627093

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.